Gene Symbol | ENC1 |
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Entrez Gene | 8507 |
Alt Symbol | CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10 |
Species | Human |
Gene Type | protein-coding |
Description | ectodermal-neural cortex 1 (with BTB domain) |
Other Description | ectoderm-neural cortex protein 1|ectodermal-neural cortex 1 (with BTB-like domain)|kelch-like 35|kelch-like family member 37|kelch-like protein 37|nuclear matrix protein NRP/B|nuclear restricted protein, BTB domain-like (brain)|p53-induced gene 10 protein|tumor protein p53 inducible protein 10 |
Swissprots | O75464 E9PFU0 O14682 B4DHJ1 Q9UPG9 |
Accessions | EAW95740 O14682 AF005381 AAC64498 AF010314 AAC39532 AF059611 AAC26109 AK096578 BAG53327 AK295128 BAG58153 AK299624 BAG61552 AK312608 BAG35496 AU120246 AY049781 AAL15438 BC000418 AAH00418 BT007392 AAP36056 DA032687 DA498140 DA785554 DQ891845 ABM82771 DQ895033 ABM85959 EU831625 ACE87225 EU831710 ACE86544 XM_011543696 XP_011541998 XM_011543697 XP_011541999 NM_001256574 NP_001243503 NM_001256575 NP_001243504 NM_001256576 NP_001243505 NM_003633 NP_003624 NR_046318 |
Function | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin- mediated proteasomal degradation mechanism. {ECO:0000269|PubMed:19424503}. |
Subcellular Location | Nucleus matrix {ECO:0000269|PubMed:19424503}. Cytoplasm {ECO:0000269|PubMed:19424503}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19424503}. |
Tissue Specificity | Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. May be down- regulated in neuroblastoma tumors. |
ENC1 (H-42) - sc-292234 from Santa Cruz Biotechnology
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ENC1 (S-13) - sc-107205 from Santa Cruz Biotechnology
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ENC1 (E-16) - sc-107203 from Santa Cruz Biotechnology
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ENC1 (7) - sc-135896 from Santa Cruz Biotechnology
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Anti-ENC1 antibody - ab106683 from Abcam
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Anti-ENC1 antibody - ab130588 from Abcam
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Anti-ENC1 antibody - ab157258 from Abcam
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Anti-ENC1 antibody - ab56348 from Abcam
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Anti-ENC1 antibody [EPR5406(B)] - ab124902 from Abcam
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Anti-ENC1 Antibody (aa17-98) - LS-C124949 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa17-99, clone 10C73, Azide-free) - LS-C183593 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423, AP) - LS-C256668 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423, Biotin) - LS-C256670 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423, APC) - LS-C256669 from LifeSpan Bioscience
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Anti-ENC1 Antibody (N-Terminus) - LS-C109872 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423, FITC) - LS-C256671 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423, Azide-free, HRP) - LS-C256672 from LifeSpan Bioscience
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Anti-ENC1 Antibody (clone 3C10) - LS-C139302 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423, PE) - LS-C256673 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa394-423) - LS-C321110 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa395-423) - LS-C167758 from LifeSpan Bioscience
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Anti-ENC1 Antibody (Internal, clone EPR5406(B)) - LS-C138873 from LifeSpan Bioscience
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Anti-ENC1 Antibody (Internal) - LS-C108699 from LifeSpan Bioscience
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Anti-ENC1 Antibody (aa452-464) IHC-plus⢠- LS-B9563 from LifeSpan Bioscience
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ENC1 Antibody - NBP1-77146 from Novus Biologicals
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