ZNF521

Gene Symbol ZNF521
Entrez Gene 25925
Alt Symbol EHZF, Evi3
Species Human
Gene Type protein-coding
Description zinc finger protein 521
Other Description LYST-interacting protein 3|early hematopoietic zinc finger protein
Swissprots Q96K83 B0YJB7 Q8TES6 Q9C065 Q8IXI0 Q9HAL5 Q9UFK4
Accessions ACA06095 EAX01201 Q96K83 AF141339 AAG49442 AJ518106 CAD57322 AK021452 BAB13829 AK027354 BAB55056 AK074046 BAB84872 AK293067 BAF85756 AL117615 CAB56016 BC032869 AAH32869 BC113622 AAI13623 BC113648 AAI13649 BC143727 CA415157 DA102816 XM_005258241 XP_005258298 XM_011525909 XP_011524211 XM_011525910 XP_011524212 XM_011525911 XP_011524213 NM_001308225 NP_001295154 NM_015461 NP_056276
Function Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes. {ECO:0000269|PubMed:14630787}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Predominantly expressed in hematopoietic cells. Present in organs and tissues that contain stem and progenitor cells, myeloid and/or lymphoid: placenta, spleen, lymph nodes, thymus, bone marrow and fetal liver. Within the hematopoietic system, it is abundant in CD34(+) cells but undetectable in mature peripheral blood leukocytes, and its levels rapidly decrease during the differentiation of CD34(+) cells in response to hemopoietins. {ECO:0000269|PubMed:14630787}.

EHZF (S-15) - sc-84808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
EHZF (S-15): sc-84808. Immunoperoxidase staining of formalin fixed, paraffin-embedded human seminal vesicle tissue showing nuclear and cytoplasmic staining of glandular cells.

EHZF (Y-19) - sc-84809 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 antibody - ab156271 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of ZNF521 in HeLa cells with ab156271 at 20 ug/mL.

Anti-ZNF521 antibody - ab113835 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab113835, at 5µg/ml, staining ZNF521 in formalin-fixed, paraffin-embedded Human Small Intestine tissue by Immunohistochemistry.

Anti-ZNF521 antibody - ab181751 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 antibody - ab140195 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling ZNF521 with ab140195 at 5 µg/ml.

Anti-ZNF521 antibody - N-terminal - ab189956 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZNF521 antibody - N-terminal (ab189956) at 1 µg/mlLane 1 : HeLa cell lysateLane 2 : HeLa cell lysate with blocking peptide

Anti-ZNF521 Antibody - LS-C150737 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (DY650) - LS-C180986 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody - LS-C150736 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (Biotin) - LS-C180985 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody - LS-C145173 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (DY488) - LS-C180987 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (Biotin) - LS-C180990 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (HRP) - LS-C180988 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (DY488) - LS-C180992 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (DY550) - LS-C180994 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (DY550) - LS-C180989 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (HRP) - LS-C180993 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (DY650) - LS-C180991 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (C-Terminus) - LS-C305892 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ZNF521 Antibody (C-Terminus) IHC-plus™ - LS-B4732 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ZNF521 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4732 concentration 5 ug/ml.

Anti-ZNF521 Antibody (N-Terminus) IHC-plus™ - LS-B8828 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ZNF521 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ZNF521 Antibody - NBP1-91270 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZNF521 Antibody [NBP1-91270] - Zfp521 antibody was tested in U2OS cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

ZNF521 Antibody - NBP1-91271 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZNF521 Antibody [NBP1-91271] - Zfp521 antibody was tested in U2OS cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
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