SMC1B

Gene Symbol	SMC1B
Entrez Gene	27127
Alt Symbol	SMC1BETA, SMC1L2
Species	Human
Gene Type	protein-coding
Description	structural maintenance of chromosomes 1B
Other Description	SMC protein 1B|SMC1 (structural maintenance of chromosomes 1, yeast)-like 1|SMC1 structural maintenance of chromosomes 1-like 2|mitosis-specific chromosome segregation protein like protein beta|structural maintenance of chromosomes protein 1B
Swissprots	B0QY23 Q9Y3G5 Q8NDV3 A0AV46 Q6ZUF9 B0QY24 Q5TIC3
Accessions	EAW73381 EAW73382 EAW73383 Q8NDV3 AJ504806 CAD43404 AK125736 BAC86266 AL704843 BC126208 AAI26209 BG194018 XM_011530144 XP_011528446 XM_011530145 XP_011528447 XM_011530146 XP_011528448 XR_244368 NM_001291501 NP_001278430 NM_148674 NP_683515
Function	Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Note=Associates with chromatin. In prophase I stage of meiosis, localizes along the AE of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. Remains chromatin associated at the centromeres up to metaphase II. At anaphase II, dissociates from centromeres, allowing chromosomes segregation (By similarity). {ECO:0000250}.
Top Pathways	Cell cycle, Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

structural maintenance of chromosomes 1B, ELISA Kit - MBS9328004 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.625 ng/ml - 20 ng/ml.

Human SMC1B ELISA Kit - E098113 from Biobool Category ELISA Kit

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9359683 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9360285 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9353088 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9350854 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9366860 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9368299 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9360018 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9362622 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9360891 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9345416 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9349837 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9358774 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9368231 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9346529 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9343455 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9360294 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9378510 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9358857 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9357846 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9355829 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes 1B (SMC1B), ELISA Kit - MBS9353216 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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