Gene Symbol | CYP2U1 |
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Entrez Gene | 113612 |
Alt Symbol | P450TEC, SPG49, SPG56 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily U, polypeptide 1 |
Other Description | cytochrome P450 2U1|spastic paraplegia 49 |
Swissprots | B2RMV7 Q96EQ6 Q7Z449 |
Accessions | EAX06215 EAX06216 EAX06217 Q7Z449 AK026498 AK290002 BAF82691 AK298989 BAG61081 AK303284 BAG64362 AK304724 BAG65487 AY343323 AAQ21380 BC012027 AAH12027 BC132767 AAI32768 BC136483 AAI36484 BC144148 BU838483 BX354124 BX437421 CD672608 HQ258621 ADR83373 XM_005262717 XP_005262774 XM_005262720 XP_005262777 NM_183075 NP_898898 |
Function | Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. {ECO:0000269|PubMed:14660610}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:14660610}; Multi-pass membrane protein {ECO:0000269|PubMed:14660610}. Microsome membrane {ECO:0000269|PubMed:14660610}. |
Tissue Specificity | Widely expressed with stronger expression in thymus, heart and cerebellum. {ECO:0000269|PubMed:14660610, ECO:0000269|PubMed:14975754, ECO:0000269|PubMed:15752708}. |
Top Pathways | Arachidonic acid metabolism |
CYP2U1 (N-12) - sc-48991 from Santa Cruz Biotechnology
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CYP2U1 (B-5) - sc-393071 from Santa Cruz Biotechnology
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CYP2U1 (D-4) - sc-393368 from Santa Cruz Biotechnology
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CYP2U1 (H-50) - sc-99215 from Santa Cruz Biotechnology
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Anti-CYP2U1 antibody - ab65128 from Abcam
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Anti-CYP2U1 antibody - ab168202 from Abcam
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Anti-CYP2U1 Antibody (aa270-319) - LS-C145573 from LifeSpan Bioscience
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Anti-CYP2U1 Antibody (aa281-330) IHC-plus™ - LS-B9673 from LifeSpan Bioscience
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Anti-CYP2U1 Antibody (aa457-473) - LS-C313146 from LifeSpan Bioscience
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CYP2U1 Antibody - NBP1-79914 from Novus Biologicals
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CYP2U1 Antibody - NBP2-30522 from Novus Biologicals
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CYP2U1 Antibody - NBP2-30991 from Novus Biologicals
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CYP2U1 Antibody - H00113612-B01 from Novus Biologicals
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Anti-CYP2U1 (center E202) antibody produced in rabbit - SAB1300950 from Sigma-Aldrich
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Anti-CYP2U1 antibody produced in rabbit - HPA046754 from Sigma-Aldrich
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Anti-Cytochrome P450 2U1 antibody produced in rabbit - SAB4500255 from Sigma-Aldrich
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Anti-CYP2U1 antibody produced in rabbit - HPA041622 from Sigma-Aldrich
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CYP2U1 antibody - middle region (ARP61922_P050) - ARP61922_P050 from Aviva Systems Biology
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CYP2U1 Antibody (OAAF02956) - OAAF02956 from Aviva Systems Biology
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Anti -CYP2U1 (SPG49, spastic paraplegia 49) - 144620 from USBiological Life Science
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CYP2U1 antibody - 70R-10392 from Fitzgerald
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Cytochrome P450 2U1 Antibody - abx013989 from Abbexa
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Cytochrome P450 2U1 Antibody - abx007981 from Abbexa
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Cytochrome P450 2U1 Antibody - abx011994 from Abbexa
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CYP2U1 antibody - H00113612-B01 from Acris Antibodies
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