| Gene Symbol |
CYP2U1
|
| Entrez Gene |
113612
|
| Alt Symbol |
P450TEC, SPG49, SPG56
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 2, subfamily U, polypeptide 1
|
| Other Description |
cytochrome P450 2U1|spastic paraplegia 49
|
| Swissprots |
B2RMV7 Q96EQ6 Q7Z449
|
| Accessions |
EAX06215 EAX06216 EAX06217 Q7Z449 AK026498 AK290002 BAF82691 AK298989 BAG61081 AK303284 BAG64362 AK304724 BAG65487 AY343323 AAQ21380 BC012027 AAH12027 BC132767 AAI32768 BC136483 AAI36484 BC144148 BU838483 BX354124 BX437421 CD672608 HQ258621 ADR83373 XM_005262717 XP_005262774 XM_005262720 XP_005262777 NM_183075 NP_898898
|
| Function |
Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. {ECO:0000269|PubMed:14660610}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:14660610}; Multi-pass membrane protein {ECO:0000269|PubMed:14660610}. Microsome membrane {ECO:0000269|PubMed:14660610}.
|
| Tissue Specificity |
Widely expressed with stronger expression in thymus, heart and cerebellum. {ECO:0000269|PubMed:14660610, ECO:0000269|PubMed:14975754, ECO:0000269|PubMed:15752708}.
|
| Top Pathways |
Arachidonic acid metabolism
|