Gene Symbol | RASA1 |
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Entrez Gene | 5921 |
Alt Symbol | CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP |
Species | Human |
Gene Type | protein-coding |
Description | RAS p21 protein activator (GTPase activating protein) 1 |
Other Description | ras GTPase-activating protein 1|triphosphatase-activating protein |
Swissprots | Q9UDI1 B4DTL2 Q68CU6 P20936 B2R6W3 |
Accessions | EAW95931 EAW95932 EAW95933 P20936 AB209106 BAD92343 AK300263 BAG62024 AK300269 BAG62030 AK300406 BAG62136 AK312739 BAG35610 BC020761 AAH20761 BC033015 AAH33015 BC054891 AAH54891 BC070063 BC107870 BC131816 AAI31817 CF528258 CR749722 CAH18488 DA863496 M23379 AAA52517 M23612 AAA35865 XM_011543525 XP_011541827 XM_011543526 XP_011541828 XM_011543527 XP_011541829 NM_002890 NP_002881 NM_022650 NP_072179 |
Function | Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1. {ECO:0000269|PubMed:11389730, ECO:0000269|PubMed:8360177}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:8360177}. |
Tissue Specificity | In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level). {ECO:0000269|PubMed:8360177}. |
Top Pathways | Axon guidance, MAPK signaling pathway |
Human RASA1 full length protein - ab116964 from Abcam
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Human RASA1 protein fragment - ab116965 from Abcam
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RASA1-Antibody-C-term-Blocking-peptide - BP12950b from Abgent, a WuXi AppTec company
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RasGAP Blocking Peptide - 33R-10706 from Fitzgerald
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RASA1 / RasGAP - H00005921-P01-10 from Acris Antibodies
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RASA1 / RasGAP - H00005921-P01-25 from Acris Antibodies
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RASA1 / RasGAP - H00005921-Q01-10 from Acris Antibodies
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RASA1 / RasGAP - H00005921-Q01-25 from Acris Antibodies
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RASA1 / RasGAP control peptide - AP00093CP-N from Acris Antibodies
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RASA1 fusion protein - Ag3906 from Proteintech Group
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Recombinant Human RASA1 - RASA1-28974TH from Creative Biomart
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Recombinant Human RASA1 - RASA1-28975TH from Creative Biomart
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Recombinant Human RASA1, GST-tagged - RASA1-2186H from Creative Biomart
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Recombinant Ras GTPase Activating Protein 1 (RASA1) - RPB616Hu01 from Uscn Life Science Inc.
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Recombinant Ras GTPase Activating Protein 1 (RASA1) - RPB616Hu01 from Cloud-clone
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Recombinant Human Ras GTPase-activating protein 1(RASA1) ,partial - CSB-YP019346HU CSB-EP019346HU CSB-BP019346HU CSB-MP019346HU from Cusabio
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RasGAP Blocking Peptide - 3311BP-50 from Biovision
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RASA1 / RasGAP (transcript variant 1) - TP305473 from Acris Antibodies
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RasGAP, Peptide - MBS843781 from MyBioSource
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Recombinant Human RASA1 protein, MYC/DDK-tagged - RASA1-2382H from Creative Biomart
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Recombinant Human Ras GTPase-activating protein 1/RASA1, transfected HEK293 cell lysate - 230-10173-100 from RayBiotech
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Recombinant Human Ras GTPase-activating protein 1/RASA1, transfected HEK293 cell culture supernatant - 230-20140-200 from RayBiotech
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RASA1 Recombinant Protein (OPCD06608) - OPCD06608 from Aviva Systems Biology
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Ras-GAP Recombinant Protein Antigen - NBP2-56891PEP from Novus Biologicals
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Ras-GAP Recombinant Protein Antigen - NBP2-55354PEP from Novus Biologicals
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