Gene Symbol | EIF5AL1 |
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Entrez Gene | 143244 |
Alt Symbol | EIF5AP1, bA342M3.3 |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 5A-like 1 |
Other Description | eukaryotic translation initiation factor 5A pseudogene 1|eukaryotic translation initiation factor 5A-1-like |
Swissprots | Q6IS14 |
Accessions | AAD14095 Q6IS14 BC070048 AAH70048 NM_001099692 NP_001093162 |
Function | mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus, nuclear pore complex {ECO:0000250}. Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. {ECO:0000250}. |
EIF5AL1 Antibody Blocking Peptide - LS-E1348 from LifeSpan Bioscience
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EIF5AL1-Antibody-C-term-Blocking-peptide - BP11986b from Abgent, a WuXi AppTec company
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Recombinant Human Eukaryotic translation initiation factor 5A-1-like(EIF5AL1) - CSB-YP757114HU CSB-EP757114HU CSB-BP757114HU CSB-MP757114HU from Cusabio
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EIF5AL1 Peptide, Human - M34GP04843H from Creative Peptides
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Eukaryotic translation initiation factor 5A-1-like (EIF5AL1), Recombinant Protein - MBS1460948 from MyBioSource
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