Gene Symbol | NEU2 |
---|---|
Entrez Gene | 4759 |
Alt Symbol | SIAL2 |
Species | Human |
Gene Type | protein-coding |
Description | sialidase 2 (cytosolic sialidase) |
Other Description | N-acetyl-alpha-neuraminidase 2|cytosolic sialidase|neuraminidase 2|sialidase-2 |
Swissprots | Q3KNW4 Q9Y3R4 Q6NTB4 |
Accessions | AAY24360 CAB41449 EAW71028 Q9Y3R4 BC069151 AAH69151 BC107053 AAI07054 XM_011511241 XP_011509543 NM_005383 NP_005374 |
Function | Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides. {ECO:0000269|PubMed:14613940, ECO:0000269|PubMed:22228546}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1. {ECO:0000269|PubMed:10191093}. |
Top Pathways | Sphingolipid metabolism, Other glycan degradation |