Gene Symbol | NEU2 |
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Entrez Gene | 4759 |
Alt Symbol | SIAL2 |
Species | Human |
Gene Type | protein-coding |
Description | sialidase 2 (cytosolic sialidase) |
Other Description | N-acetyl-alpha-neuraminidase 2|cytosolic sialidase|neuraminidase 2|sialidase-2 |
Swissprots | Q3KNW4 Q9Y3R4 Q6NTB4 |
Accessions | AAY24360 CAB41449 EAW71028 Q9Y3R4 BC069151 AAH69151 BC107053 AAI07054 XM_011511241 XP_011509543 NM_005383 NP_005374 |
Function | Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides. {ECO:0000269|PubMed:14613940, ECO:0000269|PubMed:22228546}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1. {ECO:0000269|PubMed:10191093}. |
Top Pathways | Sphingolipid metabolism, Other glycan degradation |
Neu2 CRISPR/Cas9 KO Plasmid (h) - sc-408479 from Santa Cruz Biotechnology
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Neu2 HDR Plasmid (h) - sc-408479-HDR from Santa Cruz Biotechnology
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Neu2 Double Nickase Plasmid (h) - sc-408479-NIC from Santa Cruz Biotechnology
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Neu2 Double Nickase Plasmid (h2) - sc-408479-NIC-2 from Santa Cruz Biotechnology
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Neu2 CRISPR Activation Plasmid (h) - sc-408479-ACT from Santa Cruz Biotechnology
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Neu2 CRISPR Activation Plasmid (h2) - sc-408479-ACT-2 from Santa Cruz Biotechnology
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Neu2 Lentiviral Activation Particles (h) - sc-408479-LAC from Santa Cruz Biotechnology
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Neu2 Lentiviral Activation Particles (h2) - sc-408479-LAC-2 from Santa Cruz Biotechnology
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Neu2 siRNA (h) - sc-94978 from Santa Cruz Biotechnology
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Neu2 shRNA Plasmid (h) - sc-94978-SH from Santa Cruz Biotechnology
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Neu2 shRNA (h) Lentiviral Particles - sc-94978-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN15216 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15216 from Sigma-Aldrich
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NEU2 siRNA (Human) - CRH3159 from Cohesion Biosciences
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NEU2 RNAi - H00004759-R01 from Novus Biologicals
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shRNA set against Human NEU2 (NM_005383.2) - SHH351456 from Creative biogene
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Human NEU2 siRNA - orb263661 from Biorbyt
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NEU2 shRNA Plasmid (Human) - CHH3159 from Cohesion Biosciences
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NEU2 miRNA 3'UTR clone - MiUTR4H-TG05963 from Creative biogene
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