Gene Symbol | P4HA3 |
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Entrez Gene | 283208 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | prolyl 4-hydroxylase, alpha polypeptide III |
Other Description | 4-PH alpha-3|C-P4H alpha III|collagen prolyl 4-hydroxylase alpha(III)|procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III|prolyl 4-hydroxylase subunit alpha-3 |
Swissprots | B4DUD3 Q5JPA9 Q5EBL3 Q7Z4N8 A0AV13 |
Accessions | EAW74934 EAW74935 EAW74936 Q7Z4N8 AK300598 BAG62295 AL833965 CAI46215 AY313448 AAQ87603 AY327887 AAP97874 AY358521 AAQ88885 BC040582 BC089446 AAH89446 BC117333 AAI17334 BC126170 AAI26171 HY004548 HY188166 XM_005273924 XP_005273981 XM_011544951 XP_011543253 XM_011544952 XP_011543254 XR_949888 XR_949889 NM_001288748 NP_001275677 NM_182904 NP_878907 NR_110031 |
Function | Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. {ECO:0000269|PubMed:12874193, ECO:0000269|PubMed:14500733}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000305}. |
Tissue Specificity | Highly expressed in placenta, liver and fetal skin. Weakly expressed in fetal epiphyseal cartilage, fetal liver, fibroblast, lung and skeletal muscle. Expressed also in fibrous cap of carotid atherosclerotic lesions. {ECO:0000269|PubMed:12874193, ECO:0000269|PubMed:14500733}. |
Top Pathways | Arginine and proline metabolism |
P4HA3 (V-14) - sc-168880 from Santa Cruz Biotechnology
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Anti-P4HA3 antibody - ab101657 from Abcam
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Anti-P4HA3 antibody - N-terminal - ab139567 from Abcam
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Anti-P4HA3 Antibody (aa274-303, APC) - LS-C238612 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa274-303, Biotin) - LS-C238613 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa274-303, AP) - LS-C238611 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa274-303, FITC) - LS-C238614 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa274-303, PE) - LS-C238616 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa274-303, Azide-free, HRP) - LS-C248387 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa273-303) - LS-C323743 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa77-126) - LS-C169905 from LifeSpan Bioscience
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Anti-P4HA3 Antibody (aa274-303) - LS-C163327 from LifeSpan Bioscience
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P4HA3 Antibody - NBP1-84396 from Novus Biologicals
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P4HA3 Antibody (7F10) - H00283208-M02 from Novus Biologicals
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Anti-P4HA3 antibody produced in rabbit - HPA007897 from Sigma-Aldrich
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Monoclonal Anti-P4HA3 antibody produced in mouse - SAB1409135 from Sigma-Aldrich
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ANTI-P4HA3 (CENTER) antibody produced in rabbit - SAB1304037 from Sigma-Aldrich
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P4HA3 Antibody - N-terminal region (ARP67221_P050) - ARP67221_P050 from Aviva Systems Biology
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P4HA3-Antibody-Center - AP13685c from Abgent, a WuXi AppTec company
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P4HA3 Antibody - middle region (OAAB09985) - OAAB09985 from Aviva Systems Biology
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P4HA3 antibody - orb77765 from Biorbyt
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P4HA3 Antibody - abx027535 from Abbexa
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P4HA3 Antibody - abx038120 from Abbexa
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P4HA3 antibody - 23185-1-AP from Acris Antibodies
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P4HA3 antibody - H00283208-M02 from Acris Antibodies
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