Gene Symbol |
GTF2A1
|
Entrez Gene |
2957
|
Alt Symbol |
TF2A1, TFIIA, TFIIA-42, TFIIAL
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
general transcription factor IIA, 1, 19/37kDa
|
Other Description |
TFIIA alpha, p55|general transcription factor IIA subunit 1|glucose regulated protein, 58kD pseudogene|transcription initiation factor IIA subunit 1|transcription initiation factor TFIIA 42 kDa subunit
|
Swissprots |
P52655 Q3KNQ9
|
Accessions |
AAF26776 EAW81334 EAW81335 P52655 AK021641 AK025178 BC041410 BC050703 BC107155 AAI07156 BC107156 AAI07157 BX493028 CB240876 D14886 BAA03603 D14887 BAA03604 EU446618 ABZ92147 EU446893 ABZ92422 X75383 CAA53151 X77225 CAA54442 NM_001278940 NP_001265869 NM_015859 NP_056943 NM_201595 NP_963889
|
Function |
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. {ECO:0000269|PubMed:11030333, ECO:0000269|PubMed:16537915}.
|
Subcellular Location |
Nucleus.
|
Top Pathways |
Viral carcinogenesis, Basal transcription factors
|