Gene Symbol | GTF2A1 |
---|---|
Entrez Gene | 2957 |
Alt Symbol | TF2A1, TFIIA, TFIIA-42, TFIIAL |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIA, 1, 19/37kDa |
Other Description | TFIIA alpha, p55|general transcription factor IIA subunit 1|glucose regulated protein, 58kD pseudogene|transcription initiation factor IIA subunit 1|transcription initiation factor TFIIA 42 kDa subunit |
Swissprots | P52655 Q3KNQ9 |
Accessions | AAF26776 EAW81334 EAW81335 P52655 AK021641 AK025178 BC041410 BC050703 BC107155 AAI07156 BC107156 AAI07157 BX493028 CB240876 D14886 BAA03603 D14887 BAA03604 EU446618 ABZ92147 EU446893 ABZ92422 X75383 CAA53151 X77225 CAA54442 NM_001278940 NP_001265869 NM_015859 NP_056943 NM_201595 NP_963889 |
Function | TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. {ECO:0000269|PubMed:11030333, ECO:0000269|PubMed:16537915}. |
Subcellular Location | Nucleus. |
Top Pathways | Viral carcinogenesis, Basal transcription factors |