Gene Symbol | GTF2A1 |
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Entrez Gene | 2957 |
Alt Symbol | TF2A1, TFIIA, TFIIA-42, TFIIAL |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIA, 1, 19/37kDa |
Other Description | TFIIA alpha, p55|general transcription factor IIA subunit 1|glucose regulated protein, 58kD pseudogene|transcription initiation factor IIA subunit 1|transcription initiation factor TFIIA 42 kDa subunit |
Swissprots | P52655 Q3KNQ9 |
Accessions | AAF26776 EAW81334 EAW81335 P52655 AK021641 AK025178 BC041410 BC050703 BC107155 AAI07156 BC107156 AAI07157 BX493028 CB240876 D14886 BAA03603 D14887 BAA03604 EU446618 ABZ92147 EU446893 ABZ92422 X75383 CAA53151 X77225 CAA54442 NM_001278940 NP_001265869 NM_015859 NP_056943 NM_201595 NP_963889 |
Function | TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. {ECO:0000269|PubMed:11030333, ECO:0000269|PubMed:16537915}. |
Subcellular Location | Nucleus. |
Top Pathways | Viral carcinogenesis, Basal transcription factors |
TFIIA-α CRISPR/Cas9 KO Plasmid (h) - sc-406062 from Santa Cruz Biotechnology
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TFIIA-α HDR Plasmid (h) - sc-406062-HDR from Santa Cruz Biotechnology
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TFIIA-α Double Nickase Plasmid (h) - sc-406062-NIC from Santa Cruz Biotechnology
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TFIIA-α Double Nickase Plasmid (h2) - sc-406062-NIC-2 from Santa Cruz Biotechnology
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TFIIA-α CRISPR Activation Plasmid (h) - sc-406062-ACT from Santa Cruz Biotechnology
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TFIIA-α CRISPR Activation Plasmid (h2) - sc-406062-ACT-2 from Santa Cruz Biotechnology
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TFIIA-α Lentiviral Activation Particles (h) - sc-406062-LAC from Santa Cruz Biotechnology
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TFIIA-α Lentiviral Activation Particles (h2) - sc-406062-LAC-2 from Santa Cruz Biotechnology
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TFIIA-α/β siRNA (h) - sc-38517 from Santa Cruz Biotechnology
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TFIIA-α shRNA Plasmid (h) - sc-38517-SH from Santa Cruz Biotechnology
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TFIIA-α shRNA (h) Lentiviral Particles - sc-38517-V from Santa Cruz Biotechnology
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GTF2A1 RNAi - H00002957-R02 from Novus Biologicals
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MISSION® esiRNA - EHU064121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9753 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9753 from Sigma-Aldrich
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GTF2A1 siRNA (Human) - CRH2000 from Cohesion Biosciences
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GTF2A1 RNAi - H00002957-R01 from Novus Biologicals
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GTF2A1 - MBS8236027 from MyBioSource
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shRNA set against Human GTF2A1 (NM_201595.2) - SHH308822 from Creative biogene
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Human GTF2A1 siRNA - orb262502 from Biorbyt
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GTF2A1 shRNA Plasmid (Human) - CHH2000 from Cohesion Biosciences
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GTF2A1 miRNA 3'UTR clone - MiUTR3H-03436 from Creative biogene
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GTF2A1 miRNA 3'UTR clone - MiUTR3H-03437 from Creative biogene
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