MBP

Gene Symbol	MBP
Entrez Gene	4155
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	myelin basic protein
Other Description	myelin A1 protein|myelin membrane encephalitogenic protein
Swissprots	B7ZKS4 A8MY86 Q6FI04 Q59GX3 B3KY66 B7ZKS2 Q6AI64 Q15339 Q6PK23 Q65ZS4 A8MYL4 Q15338 A6NI84 Q15340 Q15337 P02686 A4FU54 Q6FH37
Accessions	AAA59560 AAA72008 AAA72009 AAA72011 AAC41944 CAA35179 CAH10321 CAJ75954 CBL86565 CBX47515 CBX47516 CBX47517 CBX47518 CBX47519 CBX47520 EAW66592 EAW66593 EAW66594 EAW66595 EAW66596 EAW66597 EAW66598 EAW66599 EAW66600 P02686 AB208986 BAD92223 AK074315 AK093588 AK094611 AK095121 AK098402 AK098513 AK122594 BAG53615 AK123433 BAC85616 AK124830 BAC85961 AK126858 AK128770 BAG54728 AK128788 BAG54734 AK289893 BAF82582 AK293922 BAG57303 AK296492 BAH12372 AK314553 BC008749 AAH08749 BC030093 BC065248 AAH65248 BC068550 BC080654 AAH80654 BC101771 AAI01772 BC101773 AAI01774 BC130034 BC143348 AAI43349 BC143350 AAI43351 BG766942 BM977768 BU430656 CB153535 CB156561 CR536534 CAG38771 CR541919 CAG46717 CR627018 CAH10359 L18865 AAA72010 M13577 AAA59562 M20009 AAA59561 M30047 AAA59559 M30515 AAA59564 M30516 AAA59563 N20370 XM_011526008 XP_011524310 XM_011526009 XP_011524311 XM_011526010 XP_011524312 XM_011526011 XP_011524313 XM_011526012 XP_011524314 XR_245460 XR_245461 NM_001025081 NP_001020252 NM_001025090 NP_001020261 NM_001025092 NP_001020263 NM_001025100 NP_001020271 NM_001025101 NP_001020272 NM_002385 NP_002376 NM_001025094 NM_001025098
Function	The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non- classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T- cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. {ECO:0000269|PubMed:8544862}.
Subcellular Location	Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Tissue Specificity	MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. {ECO:0000269|PubMed:7504278}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active Myelin Basic Protein full length protein - ab792 from Abcam Category Protein Prices $239.00 Sizes 2 mg Source Native

Human Myelin Basic Protein full length protein - ab171675 from Abcam Category Protein Source E. coli Species Human

Human Myelin Basic Protein full length protein - ab43614 from Abcam Category Protein Source E. coli Species Human

Mouse Myelin Basic Protein peptide - ab40389 from Abcam Category Peptide

Myelin-Basic-Protein-87-99-human - SP3213b from Abgent, a WuXi AppTec company Category Protein Prices $150.00 Sizes 1 mg Species Human

Myelin-Basic-Protein-87-99-human - SP3213a from Abgent, a WuXi AppTec company Category Protein Prices $100.00 Sizes 500 µg Species Human

Myelin Basic Protein (OPMA04348) - OPMA04348 from Aviva Systems Biology Category Protein Prices $245.00 Sizes 1 mg

MBP E.Coli Protein (OPPA01750) - OPPA01750 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 50 µg Source E. Coli Species Escherichia coli

Human MBP protein - orb245485 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human MBP protein - orb245486 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

MBP protein - 30R-AM030 from Fitzgerald Category Protein Prices $275.00 Sizes 1 mg

Human Myelin Basic Protein Protein - abx068119 from Abbexa Category Protein Source E.coli Species Human

Human Myelin Basic Protein Protein - abx068120 from Abbexa Category Protein Source E.coli Species Human

Myelin Basic Protein (1-197, His-tag) - AR51172PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

Myelin Basic Protein (1-197, His-tag) - AR51172PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Myelin Basic Protein - BA461 from Acris Antibodies Category Protein Prices $310.00 Sizes 5 mg Source Brain Species Bovine

Myelin Basic Protein - H00004155-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Myelin Basic Protein - H00004155-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Myelin Basic Protein - 8M79 from Acris Antibodies Category Protein Prices $255.00 Sizes 1 mg Source Brain Species Human

MBP, 1-197aa, Human, His tag, E.coli - 01-P2348 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Species Human

Myelin Basic Protein (MBP), Human - 20-6755 from ARP American Research Products Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

MBP fusion protein - Ag0713 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MBP [87-99] Peptide - 350264 from ABBIOTEC Category Peptide Prices $65.00 Sizes 1 mg

MBP [1-11] Peptide - 350263 from ABBIOTEC Category Peptide Prices $65.00 Sizes 1 mg

Myelin Basic Protein - GWB-92BD80 from Genway Biotech Category Protein Prices $306.00 Sizes 1 mg

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