BTN3A1

Gene Symbol	BTN3A1
Entrez Gene	11119
Alt Symbol	BT3.1, BTF5, BTN3.1, CD277
Species	Human
Gene Type	protein-coding
Description	butyrophilin, subfamily 3, member A1
Other Description	butyrophilin subfamily 3 member A1|dJ45P21.3 (butyrophilin, subfamily 3, member A1)
Swissprots	B4DIQ1 E9PHG8 Q53F15 E9PGB4 B4DRM2 Q0P515 O00481 A2A278 Q99420 A8K2C8 Q147X5 Q9HCY1
Accessions	EAW55566 EAW55567 O00481 AA977088 AK223474 BAD97194 AK290193 BAF82882 AK291162 BAF83851 AK295720 BAG58563 AK298652 BAG60824 AK299327 BAG61334 AK311233 BC065567 BC118586 AAI18587 BC121800 AAI21801 BG744194 BM147268 BM542639 BU178206 BU617041 CA309315 CB148209 CD110416 DA044176 DC417480 T86577 U90552 AAB53430 Y07827 CAA69164 XM_005248833 XP_005248890 XM_005248834 XP_005248891 XM_006714983 XP_006715046 XM_011514272 XP_011512574 XM_011514273 XP_011512575 XR_926039 NM_001145008 NP_001138480 NM_001145009 NP_001138481 NM_007048 NP_008979 NM_194441 NP_919423
Function	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. {ECO:0000269|PubMed:21113407, ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497, ECO:0000269|PubMed:22846996}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21113407, ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497}; Single- pass type I membrane protein {ECO:0000269|PubMed:21113407, ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497}.
Tissue Specificity	Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level). Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle. {ECO:0000269|PubMed:20610803, ECO:0000269|PubMed:21113407, ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:9149941}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BTN3A1 / CD277 Antibody Blocking Peptide - LS-E2473 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BTN3A1-Antibody-C-term-Blocking-peptide - BP13499b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human CD277/BTN3A1 Fc Chimera, CF - 8539-BT-050 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived

Human BTN3A1 (Fc Tag) protein - orb232406 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Species Human

BTN3A1 fusion protein - ag18490 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

BTN3A1 fusion protein - Ag18414 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human BTN3A1, His-tagged - BTN3A1-47H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human BTN3A1, MIgG2a Fc-tagged - BTN3A1-001H from Creative Biomart Category Protein Source CHO cells Species Human

Recombinant Human BTN3A1, HIgG1 Fc-tagged - BTN3A1-002H from Creative Biomart Category Protein Source CHO cells Species Human

Human BTN3A1 / CD277 Protein (ECD, Fc Tag) - 15973-H02H-20 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Human Butyrophilin subfamily 3 member A1(BTN3A1) - CSB-EP002873HU CSB-BP002873HU CSB-MP002873HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Butyrophilin subfamily 3 member A1(BTN3A1) - CSB-YP002873HU from Cusabio Category Protein Source Yeast Species Human

Recombinant Human CD277/BTN3A1 Fc Chimera Protein, CF - 8539-BT from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Human embryonic kidney cell, HEK293-derived Human CD277/BTN3A1 (Phe31-Gly254) Accession # O00481 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

BTN3A1 (transcript variant 1) - TP316344 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human BTN3A1 Protein, Fc-tagged - BTN3A1-736H from Creative Biomart Category Protein Source HEK293 Species Human

BTN3A1 Recombinant Protein Antigen - NBP1-90750PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BTN3A1 Peptide, Human - M34GP01587H from Creative Peptides Category Peptide Source Synthetic. Species Human

BTN3A1 Recombinant Protein (OPCA01488) - OPCA01488 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

BTN3A1 Recombinant Protein (OPCA02607) - OPCA02607 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Mouse

Human BTN3A1 protein - orb358226 from Biorbyt Category Protein Prices $221.00, $366.00, $646.00, $1,071.00, $1,692.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human BTN3A1 protein - orb246884 from Biorbyt Category Protein Prices $221.00, $366.00, $646.00, $1,071.00, $1,692.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human BTN3A1 protein - orb2261 from Biorbyt Category Protein Prices $247.00, $510.00, $1,377.00, $1,896.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human BTN3A1 protein - orb383498 from Biorbyt Category Protein Prices $646.00, $3,086.00 Sizes 100 μg, 1 mg Species Human

Recombinant Human Butyrophilin subfamily 3 member A1(BTN3A1),partial - CSB-YP002873MO from Cusabio Category Protein Source Yeast Species Human

Human BTN3A1 / CD277 Protein, Fc Tag - BT1-H5255 from ACROBiosystems Category Protein Prices $315.00, $1,800.00 Sizes 100 µg, 1 mg Source Human BTN3A1 / CD277 Protein, Fc Tag, Gln 30 - Gly 254 (Accession # AAI21801) was produced in human 293 cells (HEK293) at ACROBiosystems. Species Human

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