Gene Symbol | HTATSF1 |
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Entrez Gene | 27336 |
Alt Symbol | TAT-SF1, TATSF1, dJ196E23.2 |
Species | Human |
Gene Type | protein-coding |
Description | HIV-1 Tat specific factor 1 |
Other Description | HIV TAT specific factor 1|HIV Tat-specific factor 1|cofactor required for Tat activation of HIV-1 transcription |
Swissprots | Q99730 Q59G06 O43719 D3DWG9 |
Accessions | EAW88468 EAW88469 O43719 AB209303 BAD92540 AK225870 AK299403 BAG61386 BC009896 AAH09896 BT006886 AAP35532 BU633070 EU176345 ABW03796 U76992 AAB18823 XM_005262404 XP_005262461 NM_001163280 NP_001156752 NM_014500 NP_055315 |
Function | Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus. {ECO:0000269|PubMed:10393184, ECO:0000269|PubMed:10454543, ECO:0000269|PubMed:10913173, ECO:0000269|PubMed:11420046, ECO:0000269|PubMed:11780068, ECO:0000269|PubMed:15905670, ECO:0000269|PubMed:8849451, ECO:0000269|PubMed:9765201}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15485897, ECO:0000269|PubMed:8849451}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:8849451}. |
HTATSF1 / TAT-SF1 Antibody Blocking Peptide - LS-E8360 from LifeSpan Bioscience
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HTATSF1 / TAT-SF1 Antibody Blocking Peptide - LS-E11119 from LifeSpan Bioscience
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HTATSF1 / TAT-SF1 Antibody Blocking Peptide - LS-E21214 from LifeSpan Bioscience
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HTATSF1 / TAT-SF1 Antibody Blocking Peptide - LS-E26446 from LifeSpan Bioscience
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HTATSF1-Antibody-N-term-Blocking-Peptide - BP6654a from Abgent, a WuXi AppTec company
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HTATSF1 blocking peptide - GTX88971-PEP from GeneTex
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HIV TAT Specific Factor 1 Peptide - AC21-1285-P from Abcore
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HTATSF1 Peptide - 45-752P from ProSci
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HTATSF1 fusion protein - Ag14744 from Proteintech Group
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HTATSF1 fusion protein - Ag14805 from Proteintech Group
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Recombinant Human HTATSF1, His-tagged - HTATSF1-14000H from Creative Biomart
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Recombinant Human HIV Tat-specific factor 1(HTATSF1) - CSB-YP010872HU CSB-EP010872HU CSB-BP010872HU CSB-MP010872HU from Cusabio
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HTATSF1, Peptide - MBS426301 from MyBioSource
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HIV TAT specific factor 1 Recombinant Protein Antigen - NBP1-86966PEP from Novus Biologicals
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HTATSF1-Antibody-Center-Blocking-Peptide - BP6654c from Abgent, a WuXi AppTec company
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HTATSF1 Peptide, Human - M34GP07334H from Creative Peptides
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HIV Tat-specific factor 1 (HTATSF1), Recombinant Protein - MBS1210979 from MyBioSource
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HTATSF1 Immunizing peptide - orb50283 from Biorbyt
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