Gene Symbol | CPSF1 |
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Entrez Gene | 29894 |
Alt Symbol | CPSF160, HSU37012, P/cl.18 |
Species | Human |
Gene Type | protein-coding |
Description | cleavage and polyadenylation specific factor 1, 160kDa |
Other Description | CPSF 160 kDa subunit|cleavage and polyadenylation specificity factor 160 kDa subunit|cleavage and polyadenylation specificity factor subunit 1|polyadenylation specificity factor |
Swissprots | Q10570 Q96AF0 |
Accessions | EAW82106 EAW82107 EAW82108 EAW82109 EAW82110 Q10570 AB046744 BAB21613 AK293601 BAG57065 BC009954 BC017232 AAH17232 BC028197 CD299980 DQ893479 ABM84405 DQ896356 ABM87355 U37012 AAC50293 XM_006716548 XP_006716611 XM_006716549 XP_006716612 XM_006716550 XP_006716613 XM_011516997 XP_011515299 XM_011516998 XP_011515300 XM_011516999 XP_011515301 NM_013291 NP_037423 |
Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. {ECO:0000269|PubMed:14749727}. |
Subcellular Location | Nucleus, nucleoplasm. |
Top Pathways | mRNA surveillance pathway |
CPSF1 (B-5) - sc-166282 from Santa Cruz Biotechnology
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CPSF1 (E-20) - sc-17290 from Santa Cruz Biotechnology
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CPSF1 (G-10) - sc-166281 from Santa Cruz Biotechnology
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CPSF1 (H-300) - sc-28872 from Santa Cruz Biotechnology
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CPSF1 (N-20) - sc-17289 from Santa Cruz Biotechnology
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Anti-CPSF1 antibody - ab81552 from Abcam
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Anti-CPSF1 antibody - ab84743 from Abcam
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Anti-CPSF1 antibody - ab62598 from Abcam
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Anti-CPSF160 / CPSF1 Antibody (aa1392-1442) - LS-C288371 from LifeSpan Bioscience
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Anti-CPSF160 / CPSF1 Antibody (aa531-580) - LS-C40321 from LifeSpan Bioscience
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Anti-CPSF160 / CPSF1 Antibody (aa1392-1442) - LS-C286545 from LifeSpan Bioscience
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CPSF1 Antibody - NB100-79822 from Novus Biologicals
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CPSF1 Antibody - NBP1-57434 from Novus Biologicals
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Anti-CPSF1 (C-terminal) antibody produced in rabbit - C2497 from Sigma-Aldrich
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Anti-CPSF1 (N-terminal) antibody produced in rabbit - C2622 from Sigma-Aldrich
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Anti-CPSF1 antibody produced in rabbit - AV40741 from Sigma-Aldrich
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CPSF1 antibody - middle region (ARP40741_P050) - ARP40741_P050 from Aviva Systems Biology
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CPSF1 antibody [C1C2], Internal - GTX115895 from GeneTex
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CPSF1 antibody [N1N2], N-term - GTX116001 from GeneTex
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CPSF1 antibody - orb182721 from Biorbyt
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CPSF1 antibody - 70R-16567 from Fitzgerald
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CPSF1 antibody - 70R-4864 from Fitzgerald
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CPSF1 Antibody - abx111692 from Abbexa
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CPSF1 antibody - 11031-1-AP from Acris Antibodies
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CPSF1 Antibody - 29-411 from ProSci
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