GLS2

Gene Symbol	GLS2
Entrez Gene	27165
Alt Symbol	GA, GLS, LGA, hLGA
Species	Human
Gene Type	protein-coding
Description	glutaminase 2 (liver, mitochondrial)
Other Description	L-glutamine amidohydrolase|breast cell glutaminase|glutaminase I|glutaminase liver isoform, mitochondrial|phosphate-activated glutaminase|phosphate-dependent glutaminase
Swissprots	B7Z8Q9 Q9NYY2 Q9UI31 Q8IX91 Q9UI32
Accessions	AAO13298 CCO13737 EAW96942 EAW96943 EAW96944 EAW96945 Q9UI32 AF038170 AF110329 AF110330 AAF21933 AF110331 AAF21934 AF223944 AAF33826 AF279698 AAG17701 AI241400 AK000467 AK289471 BAF82160 AK294822 BAG57935 AK303772 BAH14045 BC025661 BC036929 BC048344 BC059370 BC119767 AAI19768 BC119768 AAI19769 BC166649 AAI66649 BI916699 DA060302 DA180204 HM775422 ADR77821 HM775423 ADR77822 HM775424 ADR77823 XM_005268797 XP_005268854 NM_001280796 NP_001267725 NM_001280797 NP_001267726 NM_001280798 NP_001267727 NM_013267 NP_037399 NM_138566
Function	Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. {ECO:0000269|PubMed:20378837}.
Subcellular Location	Mitochondrion {ECO:0000269|PubMed:20378837}.
Tissue Specificity	Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas. {ECO:0000269|PubMed:10620514, ECO:0000269|PubMed:20378837}.
Top Pathways	Central carbon metabolism in cancer, MicroRNAs in cancer, Glutamatergic synapse, GABAergic synapse, Proximal tubule bicarbonate reclamation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse GLS2 / Glutaminase 2 ELISA Kit (Sandwich ELISA) - LS-F6991 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.53 ng/ml Range 1.56-100 ng/ml

Glutaminase kidney isoform, mitochondrial, GLS, Human, ELISA Kit - E15055h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.312-20 ng/mL

Human Anti-GLS ELISA Kit - HG0344 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

glutaminase 2 (liver, mitochondrial) , ELISA Kit - MBS9316115 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

GA, ELISA Kit - MBS2513425 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 11.25pmol/mL Range 18.75-1200pmol/mL

GA, ELISA Kit - MBS2507825 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 11.25ng/mL Range 18.75-1200ng/mL

GA, ELISA Kit - MBS2509113 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 3.75ng/mL Range 6.25-400ng/mL

GA, ELISA Kit - MBS2505827 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 3.75ng/mL Range 6.25-400ng/mL

GA, ELISA Kit - MBS2508905 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.563ng/mL Range 0.938-60ng/mL

GA, ELISA Kit - MBS2515424 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.45ng/mL Range 0.75-48ng/mL

Ganglioside Antibody, ELISA Kit - MBS010762 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS007435 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS038679 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS038683 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS086841 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS036425 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS013653 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0ng/ml Range 6.25ng/ml-200ng/ml

Ganglioside Antibody, ELISA Kit - MBS036438 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS073047 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS042073 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS019829 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS024438 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS021648 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS010406 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ganglioside Antibody, ELISA Kit - MBS046514 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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