Gene Symbol |
GRPR
|
Entrez Gene |
2925
|
Alt Symbol |
BB2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
gastrin-releasing peptide receptor
|
Other Description |
GRP-R|GRP-preferring bombesin receptor|bombesin receptor 2
|
Swissprots |
B2R910 P30550
|
Accessions |
AAB27329 AAL96377 EAW98909 P30550 AK313588 BAG36357 AU125660 BC074733 AAH74733 KJ534854 AHW56494 KJ534855 AHW56495 M73481 AAA88050 U57365 AAB40612 NM_005314 NP_005305
|
Function |
Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain. {ECO:0000269|PubMed:11245983}.
|
Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|