Gene Symbol | GRPR |
---|---|
Entrez Gene | 2925 |
Alt Symbol | BB2 |
Species | Human |
Gene Type | protein-coding |
Description | gastrin-releasing peptide receptor |
Other Description | GRP-R|GRP-preferring bombesin receptor|bombesin receptor 2 |
Swissprots | B2R910 P30550 |
Accessions | AAB27329 AAL96377 EAW98909 P30550 AK313588 BAG36357 AU125660 BC074733 AAH74733 KJ534854 AHW56494 KJ534855 AHW56495 M73481 AAA88050 U57365 AAB40612 NM_005314 NP_005305 |
Function | Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain. {ECO:0000269|PubMed:11245983}. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |