| Gene Symbol |
GUCA1B
|
| Entrez Gene |
2979
|
| Alt Symbol |
GCAP2, GUCA2, RP48
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanylate cyclase activator 1B (retina)
|
| Other Description |
GCAP 2|guanylate cyclase-activating protein, photoreceptor 2|guanylyl cyclase-activating protein 2
|
| Swissprots |
Q9UMX6 Q9NU15
|
| Accessions |
AAD47279 EAX04085 Q9UMX6 BC166640 AAI66640 BQ636025 BX537393 CAD97635 XM_011514540 XP_011512842 NM_002098 NP_002089
|
| Function |
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
|
| Subcellular Location |
Cell membrane. Note=Membranes of outer segment.
|
| Tissue Specificity |
Retina. Cones and rod.
|
| Top Pathways |
Olfactory transduction, Phototransduction
|
![Western Blot: GCAP2 Overexpression Lysate (Adult Normal) [NBP2-10804] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GCAP2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/25769_GCAP2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-10804-img0001.jpg)