Gene Symbol | GUCA1B |
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Entrez Gene | 2979 |
Alt Symbol | GCAP2, GUCA2, RP48 |
Species | Human |
Gene Type | protein-coding |
Description | guanylate cyclase activator 1B (retina) |
Other Description | GCAP 2|guanylate cyclase-activating protein, photoreceptor 2|guanylyl cyclase-activating protein 2 |
Swissprots | Q9UMX6 Q9NU15 |
Accessions | AAD47279 EAX04085 Q9UMX6 BC166640 AAI66640 BQ636025 BX537393 CAD97635 XM_011514540 XP_011512842 NM_002098 NP_002089 |
Function | Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure. |
Subcellular Location | Cell membrane. Note=Membranes of outer segment. |
Tissue Specificity | Retina. Cones and rod. |
Top Pathways | Olfactory transduction, Phototransduction |
Human GCAP2 protein fragment - ab158610 from Abcam
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Human pro Guanylin peptide - ab42278 from Abcam
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Human pro Guanylin peptide - ab42279 from Abcam
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Human pro Guanylin peptide - ab42284 from Abcam
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GCAP2 / GUCA1B Antibody Blocking Peptide - LS-E6647 from LifeSpan Bioscience
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GCAP2 / GUCA1B Antibody Blocking Peptide - LS-E21875 from LifeSpan Bioscience
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Recombinant Human GCAP2 Protein - H00002979-Q01 from Novus Biologicals
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GUCA1B-AntibodyN-term-Blocking-peptide - BP19456a from Abgent, a WuXi AppTec company
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GUCA1B Blocking Peptide - 33R-8497 from Fitzgerald
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GCAP2 / GUCA1B - H00002979-Q01-10 from Acris Antibodies
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GCAP2 / GUCA1B - H00002979-Q01-25 from Acris Antibodies
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Recombinant Guanylate Cyclase Activator 2A (GUCA2A) - RPG291Hu01 from Cloud-clone
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Recombinant Human Guanylyl cyclase-activating protein 2(GUCA1B) - CSB-YP890759HU CSB-EP890759HU CSB-BP890759HU CSB-MP890759HU from Cusabio
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GCAP2 / GUCA1B (N-term HIS tag) - TP760676 from Acris Antibodies
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GCAP2 Protein - NBP1-89789PEP from Novus Biologicals
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GCAP2-Antibody-C-term-Blocking-Peptide - BP1568b from Abgent, a WuXi AppTec company
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GUCA1B Peptide, Human - M34GP06769H from Creative Peptides
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Guanylyl cyclase-activating protein 2 (GUCA1B), Recombinant Protein - MBS1407365 from MyBioSource
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