SNCAIP

Gene Symbol SNCAIP
Entrez Gene 9627
Alt Symbol SYPH1, Sph1
Species Human
Gene Type protein-coding
Description synuclein, alpha interacting protein
Other Description alpha-synuclein-interacting protein|synphilin-1
Swissprots D3DSZ1 Q05BS1 Q6L985 Q9Y6H5 Q6L984 Q504U9 Q9HC59 Q1PSC2 Q49AC6 Q6L986
Accessions AAG17478 EAW48887 EAW48888 EAW48889 EAW48890 EAW48891 Q9Y6H5 AB110788 BAD19017 AB110789 BAD19018 AB110790 BAD19019 AB110791 BAD19020 AB110792 BAD19021 AB110793 BAD19022 AB110794 BAD19023 AF076929 AAD30362 AI702863 AK001617 BAA91791 AK021944 BAG51060 AK298882 BAH12894 AK299687 BAH13102 AK304646 BAH14231 AK310835 BC033743 AAH33743 BC040552 AAH40552 BC094759 AAH94759 BM908442 DQ227317 ABB51162 N21998 XM_005272138 XP_005272195 XM_005272139 XP_005272196 XM_006714734 XP_006714797 XM_011543736 XP_011542038 XM_011543737 XP_011542039 XM_011543738 XP_011542040 XM_011543739 XP_011542041 XM_011543740 XP_011542042 XM_011543741 XP_011542043 XM_011543742 XP_011542044 XM_011543743 XP_011542045 XM_011543744 XP_011542046 XM_011543745 XP_011542047 XM_011543746 XP_011542048 XM_011543747 XP_011542049 XM_011543748 XP_011542050 XM_011543749 XP_011542051 XM_011543750 XP_011542052 XM_011543751 XP_011542053 NM_001242935 NP_001229864 NM_001308100 NP_001295029 NM_001308105 NP_001295034 NM_001308106 NP_001295035 NM_001308107 NP_001295036 NM_001308108 NP_001295037 NM_001308109 NP_001295038 NM_005460 NP_005451 NR_131761 NR_131762
Function Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1. {ECO:0000269|PubMed:16595633, ECO:0000269|PubMed:19224863}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10319874, ECO:0000269|PubMed:15064394, ECO:0000269|PubMed:16595633, ECO:0000269|PubMed:19762560}. Note=Detected in cytoplasmic inclusion bodies, together with SNCA.
Tissue Specificity Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta. {ECO:0000269|PubMed:10319874, ECO:0000269|PubMed:16595633}.

synphilin-1 CRISPR/Cas9 KO Plasmid (h) - sc-406126 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 HDR Plasmid (h) - sc-406126-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 Double Nickase Plasmid (h) - sc-406126-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 Double Nickase Plasmid (h2) - sc-406126-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 CRISPR Activation Plasmid (h) - sc-406126-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 CRISPR Activation Plasmid (h2) - sc-406126-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 Lentiviral Activation Particles (h) - sc-406126-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 Lentiviral Activation Particles (h2) - sc-406126-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

synphilin-1 siRNA (h) - sc-43434 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

synphilin-1 shRNA Plasmid (h) - sc-43434-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

synphilin-1 shRNA (h) Lentiviral Particles - sc-43434-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Synphilin-1 RNAi - H00009627-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19861 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19861 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05616 from Sigma-Aldrich

Category miRNA

SNCAIP siRNA (Human) - CRH6407 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNCAIP - MBS8222926 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SNCAIP (NM_005460.2) - SHH414004 from Creative biogene

Category siRNA
Species Reactivities Human

SNCAIP shRNA Plasmid (Human) - CHH6407 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SNCAIP miRNA 3'UTR clone - MiUTR1H-09684 from Creative biogene

Species Reactivities Human
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