HOPX

Gene Symbol HOPX
Entrez Gene 84525
Alt Symbol CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO
Species Human
Gene Type protein-coding
Description HOP homeobox
Other Description homeodomain-only protein|lung cancer-associated Y protein|not expressed in choriocarcinoma clone 1|not expressed in choriocarcinoma protein 1|odd homeobox 1 protein|odd homeobox protein 1
Swissprots E9PB55 Q96CI1 Q9BPY8 Q8N0V6 G3V294 A8K0Z2
Accessions EAX05503 EAX05505 EAX05511 Q9BPY8 AA504137 AB019573 AB059408 BAB40926 AB059409 BAB40927 AB059410 BAB40928 AF454763 AAL56613 AF492675 AAM46827 AF492676 AAM46828 AF492677 AAM46829 AF492678 AAM46830 AF492679 AAM46831 AF492680 AAM46832 AF492681 AAM46833 AK096707 AK123318 AK289707 BAF82396 AM393649 CAL38525 AW955211 BC014225 AAH14225 CB996541 CK002567 DA512059 DB180848 DQ892193 ABM83119 EB386856 EU176669 ABW03470 XM_006714051 XP_006714114 XM_006714052 XP_006714115 XM_011534407 XP_011532709 XM_011534408 XP_011532710 NM_001145459 NP_001138931 NM_001145460 NP_001138932 NM_032495 NP_115884 NM_139211 NP_631957 NM_139212 NP_631958
Function Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma. {ECO:0000269|PubMed:12573257, ECO:0000269|PubMed:12759545}.

Hop (E-1) - sc-398703 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Hop (E-1): sc-398703. Western blot analysis of Hop expression in non-transfected: sc-117752 (A) and mouse Hop transfected: sc-120878 (B) 293T whole cell lysates and human placenta tissue extract (C).

Hop (C-15) - sc-25146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Hop (FL-73) - sc-30216 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Hop (FL-73): sc-30216. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

Anti-HOPX antibody - ab57832 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57832 HOPX antibody at 1ug/ml.

Anti-HOPX antibody - N-terminal - ab200454 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HOPX antibody - N-terminal (ab200454) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-HOPX / HOP Antibody (aa46-73, APC) - LS-C258729 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody (aa46-73, AP) - LS-C258730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody (aa46-73, PE) - LS-C258734 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody (aa46-73, Azide-free, HRP) - LS-C258733 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody (aa46-73, FITC) - LS-C258732 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody (aa46-73, Biotin) - LS-C258731 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody - LS-C308285 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HOPX / HOP Antibody (aa46-73) - LS-C322033 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOPX / HOP Antibody (aa39-67) IHC-plus™ - LS-B10925 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-HOPX / HOP antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10925 dilution 1:100.

Anti-HOPX / HOP Antibody (N-Terminus) - LS-C336273 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of HOPX in human heart tissue with HOPX antibody at 5 ug/mL.

HOP Antibody (DS14F5) - NBP1-97503 from Novus Biologicals

Prices $279.00, $469.00
Sizes 50 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone DS14F5

HOP Antibody - NBP1-92003 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: HOP Antibody [NBP1-92003] - Staining of human skin shows moderate cytoplasmic and nuclear positivity in epidermal cells.

HOP Antibody - H00084525-B01 from Novus Biologicals

Prices $359.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HOP Antibody [H00084525-B01] - analysis of HOP expression in transfected 293T cell line by HOP MaxPab polyclonal antibody (B01). Lane 1: HOP transfected lysate (8.14 KDa). Lane 2: Non-transfected lysate.

HOP Antibody (3D6) - H00084525-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D6
ELISA: HOP Antibody (3D6) [H00084525-M01] - Detection limit for recombinant GST tagged HOP is approximately 3ng/ml as a capture antibody.

HOP Antibody - H00084525-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HOP Antibody [H00084525-B02] - analysis of HOP expression in transfected 293T cell line by HOP MaxPab polyclonal antibody (B02). Lane 1: HOP transfected lysate (8.30 KDa). Lane 2: Non-transfected lysate.

HOP Antibody - H00084525-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

JAKMIP2 Polyclonal Antibody - bs-6814R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LAGY Polyclonal Antibody - bs-9462R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Human Hela cells probed with HOPX Polyclonal Antibody, A488 conjugated (bs-9462R-A488) (green) at 1:100 for 30 minutes compared to unstained cells (blue) and isotype control (orange).

Monoclonal Anti-HOP antibody produced in mouse - WH0084525M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D6
<B>Immunoblotting</B><BR/>Monoclonal Anti-HOP, <B>Cat. No. WH0084525M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~33.77 kDa using immunogen protein lysate.

ANTI-HOPX(C-TERMINAL) antibody produced in rabbit - SAB1306944 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HOPX (C-term): <B>Cat. No. SAB1306944</B>: HOPX Antibody (C-term) western blot analysis in Ramos,A2058,293 cell line lysates (35 μg/lane).
Search more