HOPX

Gene Symbol	HOPX
Entrez Gene	84525
Alt Symbol	CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO
Species	Human
Gene Type	protein-coding
Description	HOP homeobox
Other Description	homeodomain-only protein|lung cancer-associated Y protein|not expressed in choriocarcinoma clone 1|not expressed in choriocarcinoma protein 1|odd homeobox 1 protein|odd homeobox protein 1
Swissprots	E9PB55 Q96CI1 Q9BPY8 Q8N0V6 G3V294 A8K0Z2
Accessions	EAX05503 EAX05505 EAX05511 Q9BPY8 AA504137 AB019573 AB059408 BAB40926 AB059409 BAB40927 AB059410 BAB40928 AF454763 AAL56613 AF492675 AAM46827 AF492676 AAM46828 AF492677 AAM46829 AF492678 AAM46830 AF492679 AAM46831 AF492680 AAM46832 AF492681 AAM46833 AK096707 AK123318 AK289707 BAF82396 AM393649 CAL38525 AW955211 BC014225 AAH14225 CB996541 CK002567 DA512059 DB180848 DQ892193 ABM83119 EB386856 EU176669 ABW03470 XM_006714051 XP_006714114 XM_006714052 XP_006714115 XM_011534407 XP_011532709 XM_011534408 XP_011532710 NM_001145459 NP_001138931 NM_001145460 NP_001138932 NM_032495 NP_115884 NM_139211 NP_631957 NM_139212 NP_631958
Function	Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity	Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma. {ECO:0000269|PubMed:12573257, ECO:0000269|PubMed:12759545}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HOPX full length protein - ab130041 from Abcam Category Protein Source E. coli Species Human

Human HOPX full length protein - ab125982 from Abcam Category Protein Source E. coli Species Human

HOPX / HOP Antibody Blocking Peptide - LS-E1000 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HOP Recombinant Protein - H00084525-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HOP Protein - NBP1-98893 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

HOPX-Antibody-C-term-Blocking-peptide - BP11455b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HOPX protein - orb168511 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Hip/ST13 protein - 30R-1247 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

HOPX protein (His tag) - 80R-2382 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Homeodomain-only protein / HOP (1-73, His-tag) - AR50463PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Homeodomain-only protein / HOP (1-73, His-tag) - AR50463PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Homeodomain-only protein / HOP - H00084525-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Homeodomain-only protein / HOP - H00084525-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HOPX, 1-73aa, Human, His tag, E.coli - 01-P1639 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

HOPX Peptide - 8143P from ProSci Category Peptide Species Human

HOPX fusion protein - Ag1979 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HOPX Human - PRPS-1165 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

STIP1 Human - PRPS-760 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human HOP Protein - BP002667-PRO-1158 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

HOPX, 1-73aa, Recombinant Protein - GWB-P0399I from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human HOP Homeobox, His-tagged - HOPX-6951H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human HOPX, GST-tagged - HOPX-13885H from Creative Biomart Category Protein Source E.coli Species Human

STIP1 Human - NKX-187 from Reagent Proteins Category Protein Prices $348.00, $5,685.00 Sizes 10.00 µg, 1 mg Source E.coli Species Human

Recombinant Stress Induced Phosphoprotein 1 (STIP1) - RPH120Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Homeodomain-only protein(HOPX) - CSB-YP859411HU CSB-EP859411HU CSB-BP859411HU CSB-MP859411HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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