SLC47A2

Gene Symbol SLC47A2
Entrez Gene 146802
Alt Symbol MATE2, MATE2-B, MATE2-K, MATE2K
Species Human
Gene Type protein-coding
Description solute carrier family 47 (multidrug and toxin extrusion), member 2
Other Description H+/organic cation antiporter|MATE-2|hMATE-2|kidney-specific H(+)/organic cation antiporter|multidrug and toxin extrusion 2|multidrug and toxin extrusion protein 2|solute carrier family 47, member 2
Swissprots Q96NA1 Q86VL8 Q63HJ9 Q8IV44 A0P8Z7 A0JBX9
Accessions EAW50901 EAW50902 EAW50903 EAW50904 EAW50905 EAW50906 EAW50907 Q86VL8 AB250364 BAF36847 AB250701 BAF37007 AK055758 AK096080 AK123589 AK307647 AK310218 BC035288 AAH35288 BC050578 AAH50578 BC062614 BG432484 BM924669 BM930596 BX648861 CAH56154 DA312379 XM_006721455 XP_006721518 XM_006721457 XP_006721520 XM_011523672 XP_011521974 XM_011523673 XP_011521975 XM_011523674 XP_011521976 XM_011523675 XP_011521977 XR_243543 XR_933998 XR_933999 XR_934000 XR_934001 NM_001099646 NP_001093116 NM_001256663 NP_001243592 NM_152908 NP_690872
Function Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. {ECO:0000269|PubMed:16807400, ECO:0000269|PubMed:16996621, ECO:0000269|PubMed:17509534}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localized at the brush border membranes of the proximal tubules.
Tissue Specificity Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain. {ECO:0000269|PubMed:16807400}.

MATE2 (H-60) - sc-367725 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MATE2 (H-60): sc-367725. Western blot analysis of MATE2 expression in MCF7 whole cell lysate.

MATE2 (K-13) - sc-133393 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MATE2 (K-13): sc-133393. Western blot analysis of MATE2 expression in Jurkat whole cell lysate.

MATE2 (L-13) - sc-133394 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

MATE2 (T-12) - sc-133395 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 antibody - ab105050 from Abcam

Host Rabbit
Clonality Polyclonal
IHC image of SLC47A2 staining in human kidney formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab105050, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-SLC47A2 antibody - ab106117 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IHC image of SLC47A2 staining in human kidney formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab106117, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-SLC47A2 antibody - ab128823 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-SLC47A2 antibody (ab128823) at 0.3 µg/ml (incubation time: 1 hour) + Human testis lysates in RIPA buffer at 35 µg

Anti-SLC47A2 antibody - N-terminal - ab174344 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SLC47A2 antibody - N-terminal (ab174344) at 1/100 dilutionLane 1 : Mouse kidney tissue lysateLane 2 : A2058 cell line lysateLysates/proteins at 35 µg per lane.

Anti-SLC47A2 Antibody (aa125-153, APC) - LS-C240345 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa511-524) - LS-C154833 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa125-153, AP) - LS-C240346 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa125-153, Biotin) - LS-C240348 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa125-153, FITC) - LS-C240347 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa125-153, PE) - LS-C240351 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa125-153, Azide-free, HRP) - LS-C248070 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (aa132-161) - LS-C324890 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC47A2 Antibody (C-Terminus) - LS-C82688 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SLC47A2 Antibody (aa125-153) - LS-C162843 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
S47A2 Antibody western blot of mouse kidney tissue and A2058 cell line lysates (35 ug/lane). The S47A2 antibody detected the S47A2 protein (arrow).

Anti-SLC47A2 Antibody (aa546-560) IHC-plus™ - LS-B10467 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human, Kidney: Formalin-Fixed Paraffin-Embedded (FFPE)

SLC47A2 Antibody - NBP2-38948 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SLC47A2 Antibody [NBP2-38948] - Staining of human kidney shows moderate membranous positivity in cells in tubules.

SLC47A2 Antibody - NBP1-97763 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SLC47A2 Antibody [NBP1-97763] (0.3ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SLC47A2 Antibody - NBP1-97761 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SLC47A2 Antibody [NBP1-97761] - (0.1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SLC47A2 antibody produced in rabbit - HPA044412 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC47A2: <B>Cat. No. HPA044412</B>: Immunohistochemical staining of human rectum shows strong cytoplasmic and nuclear positivity in glandular cells.

Anti-SLC47A2 antibody produced in rabbit - SAB2102219 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC47A2: <B>Cat. No.SAB2102219</B>: SLC47A2 in Fetal Lung tissue lysate with SLC47A2 antibody at 1.0 μg/mL.

ANTI-S47A2 (N-TERM) antibody produced in rabbit - SAB1304168 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-S47A2 (N-term): <B>Cat. No. SAB1304168</B>: S47A2 Antibody (N-term) western blot analysis in cell line lysates (35 μg/lane).<BR/><B>Lanes:</B><BR/>1. mouse kidney tissue<BR/>2. A2058
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