SLC47A2

Gene Symbol SLC47A2
Entrez Gene 146802
Alt Symbol MATE2, MATE2-B, MATE2-K, MATE2K
Species Human
Gene Type protein-coding
Description solute carrier family 47 (multidrug and toxin extrusion), member 2
Other Description H+/organic cation antiporter|MATE-2|hMATE-2|kidney-specific H(+)/organic cation antiporter|multidrug and toxin extrusion 2|multidrug and toxin extrusion protein 2|solute carrier family 47, member 2
Swissprots Q96NA1 Q86VL8 Q63HJ9 Q8IV44 A0P8Z7 A0JBX9
Accessions EAW50901 EAW50902 EAW50903 EAW50904 EAW50905 EAW50906 EAW50907 Q86VL8 AB250364 BAF36847 AB250701 BAF37007 AK055758 AK096080 AK123589 AK307647 AK310218 BC035288 AAH35288 BC050578 AAH50578 BC062614 BG432484 BM924669 BM930596 BX648861 CAH56154 DA312379 XM_006721455 XP_006721518 XM_006721457 XP_006721520 XM_011523672 XP_011521974 XM_011523673 XP_011521975 XM_011523674 XP_011521976 XM_011523675 XP_011521977 XR_243543 XR_933998 XR_933999 XR_934000 XR_934001 NM_001099646 NP_001093116 NM_001256663 NP_001243592 NM_152908 NP_690872
Function Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. {ECO:0000269|PubMed:16807400, ECO:0000269|PubMed:16996621, ECO:0000269|PubMed:17509534}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localized at the brush border membranes of the proximal tubules.
Tissue Specificity Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain. {ECO:0000269|PubMed:16807400}.

MATE2 CRISPR/Cas9 KO Plasmid (h) - sc-404811 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 HDR Plasmid (h) - sc-404811-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 Double Nickase Plasmid (h) - sc-404811-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 Double Nickase Plasmid (h2) - sc-404811-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 CRISPR Activation Plasmid (h) - sc-404811-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 CRISPR Activation Plasmid (h2) - sc-404811-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 Lentiviral Activation Particles (h) - sc-404811-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 Lentiviral Activation Particles (h2) - sc-404811-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MATE2 siRNA (h) - sc-93948 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MATE2 shRNA Plasmid (h) - sc-93948-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MATE2 shRNA (h) Lentiviral Particles - sc-93948-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU059051 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19649 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19649 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03831 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03831

SLC47A2 siRNA (Human) - CRJ5491 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC47A2 - MBS8211397 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC47A2 (NM_152908.3) - SHH411476 from Creative biogene

Category siRNA
Species Reactivities Human

SLC47A2 shRNA Plasmid (Human) - CHJ5491 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC47A2 miRNA 3'UTR clone - MiUTR1H-06120 from Creative biogene

Species Reactivities Human

SLC47A2 miRNA 3'UTR clone - MiUTR3H-10829 from Creative biogene

Species Reactivities Human
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