NTRK3

Gene Symbol	NTRK3
Entrez Gene	4916
Alt Symbol	GP145-TrkC, TRKC, gp145(trkC)
Species	Human
Gene Type	protein-coding
Description	neurotrophic tyrosine kinase, receptor, type 3
Other Description	ETS related protein-neurotrophic receptor tyrosine kinase fusion protein|ETV6-NTRK3 fusion|NT-3 growth factor receptor|tyrosine kinase receptor C
Swissprots	Q16288 Q12827 Q16289 O75682 H0YND1 E9PG56 B7Z4C5
Accessions	CAA12029 EAX01989 EAX01990 EAX01991 EAX01992 EAX01993 Q16288 AF052184 AF058389 AAC97478 AF058390 AAC97479 AF125808 AAF19762 AI613045 AK297160 BAH12511 AK302504 BAH13730 AK309695 AK313646 AL134171 AY065844 AAL40893 BC013693 AAH13693 BC128249 BG741347 BI962878 BM675026 BM887782 BQ893817 BT007291 AAP35955 CB053605 CK903553 DA789502 DQ323597 ABD27898 KJ534904 AHW56544 KJ534905 AHW56545 KJ534906 AHW56546 KJ535052 AHW56691 S76475 AAB33111 S76476 AAB33112 U05012 AAA75374 XM_006720543 XP_006720606 XM_006720544 XP_006720607 XM_006720545 XP_006720608 XM_006720546 XP_006720609 XM_006720547 XP_006720610 XM_006720548 XP_006720611 XM_006720549 XP_006720612 XM_006720550 XP_006720613 XM_011521634 XP_011519936 XM_011521635 XP_011519937 XM_011521636 XP_011519938 XM_011521637 XP_011519939 XM_011521638 XP_011519940 XR_931841 XR_931842 NM_001007156 NP_001007157 NM_001012338 NP_001012338 NM_001243101 NP_001230030 NM_002530 NP_002521
Function	Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.
Top Pathways	Neurotrophin signaling pathway, Central carbon metabolism in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human TrkC protein fragment - ab85274 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Active human TrkC protein fragment - ab196087 from Abcam Category Protein Prices $891.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human TrkC protein fragment - ab174034 from Abcam Category Protein Prices $372.00 Sizes 100 µg Source HEK 293 cells Species Human

TrkC protein (Fc Chimera) - ab85599 from Abcam Category Protein Source HEK 293 cells Species Human

Human TrkC protein fragment - ab159017 from Abcam Category Protein Source Wheat germ Species Human

NTRK3 / TRKC Antibody Blocking Peptide - LS-E3446 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NTRK3 / TRKC Antibody Blocking Peptide - LS-E18476 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NTRK3 / TRKC Antibody Blocking Peptide - LS-E9192 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TrkC Partial Recombinant Protein - H00004916-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TrkC Recombinant Protein - P4787 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

TrkC Peptide - P2731 from Novus Biologicals Category Peptide Species Human

NTRK3-Antibody-C-term-Blocking-Peptide - BP6818b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TRKC-Antibody-N-term-Blocking-Peptide - BP7688a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human TrkC Fc Chimera - 373-TC-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human TrkC Fc Chimera, CF - 373-TC-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human TrkC Fc His tag protein - orb83147 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human TrkC His tag protein - orb83148 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

NTRK3 Blocking Peptide - 33R-2709 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TrkC - H00004916-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TrkC - H00004916-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TrkC - P4787 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

TrkC - P5806 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

NTRK3 Recombinant Protein - 96-753 from ProSci Category Protein Source HEK293 cells Species Human

NTRK3 Recombinant Protein - 96-754 from ProSci Category Protein Source HEK293 cells Species Human

NTRK3 fusion protein - ag2635 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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