CC2D1A

Gene Symbol CC2D1A
Entrez Gene 54862
Alt Symbol FREUD-1, Freud-1/Aki1, MRT3
Species Human
Gene Type protein-coding
Description coiled-coil and C2 domain containing 1A
Other Description Akt kinase-interacting protein 1|FRE under dual repression-binding protein 1|coiled-coil and C2 domain-containing protein 1A|five prime repressor element under dual repression-binding protein 1|five repressor element under dual repression-binding protein 1|mental retardation, nonsyndromic, autosomal recessive, 3|putative NF-kappa-B-activating protein 023N|putative NFkB activating protein
Swissprots Q9NXI1 Q9H603 Q8NF89 Q86XV0 Q7Z435 Q6P1N0
Accessions EAW84380 Q6P1N0 AB097002 BAC77355 AF536205 AAN04488 AK000248 BAA91029 AK023399 BAB14561 AK026371 BAB15464 AK123155 AK315068 BC006556 BC048345 AAH48345 BC064981 AAH64981 BC113968 AAI13969 BP395853 DB065701 XM_005259972 XP_005260029 XM_005259973 XP_005260030 XM_005259974 XP_005260031 XM_005259975 XP_005260032 NM_017721 NP_060191
Function Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis. {ECO:0000250, ECO:0000269|PubMed:20171170}.
Subcellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Freud-1 (H-119) - sc-367484 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Freud-1 (K-19) - sc-79482 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Freud-1 (K-19): sc-79482. Western blot analysis of Freud-1 expression in U-251-MG (A), A549 (B) and Hep G2 (C) whole cell lysates.

Freud-1 (P-16) - sc-79483 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Freud-1 (P-16): sc-79483. Western blot analysis of Freud-1 expression in Daudi (A) and U-251-MG (B) whole cell lysates.

Freud-1 (Q-19) - sc-79484 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CC2D1A antibody - ab70375 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling CC2D1A with ab70375 at 1/1000 (1µg/ml). Detection: DAB.

Anti-CC2D1A antibody - ab68302 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CC2D1A antibody (ab68302) at 1/500 dilution + human liver tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-CC2D1A antibody - ab87279 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab87279, at a 1/250 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human breast carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

Anti-CC2D1A antibody - ab123590 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CC2D1A antibody (ab123590) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-CC2D1A antibody [EPR18421] - ab191472 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone EPR18421
All lanes : Anti-CC2D1A antibody [EPR18421] (ab191472) at 1/20000 dilutionLane 1 : Hela (Human epithelial cells from cervix adenocarcinoma) whole cell lysatesLane 2 : HEK-293 (Human epithelial cells from embryonic kidney) whole cell lysatesLane 3 : Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysatesLane 4 : MCF7 (Human breast adenocarcinoma cell line) whole cell lysatesLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/1000 dilution

Anti-CC2D1A Antibody - LS-C309741 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody - LS-C309742 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa142-172) - LS-C320033 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa143-172) - LS-C168374 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CC2D1A Antibody western blot of K562 cell line lysates (35 ug/lane). The CC2D1A antibody detected the CC2D1A protein (arrow).

Anti-CC2D1A Antibody (aa1-50) - LS-C287191 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CC2D1A by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-CC2D1A used at a dilution of 1:1000 (1 ug/ml).

Anti-CC2D1A Antibody (aa1-50) - LS-C286646 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CC2D1A by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma Antibody: Affinity purified rabbit anti-CC2D1A7 used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.

Anti-CC2D1A Antibody (aa143-172, APC) - LS-C253511 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa143-172, AP) - LS-C253512 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa143-172, Biotin) - LS-C253513 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa143-172, FITC) - LS-C253514 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa143-172, PE) - LS-C253517 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody (aa143-172, Azide-free, HRP) - LS-C253515 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CC2D1A Antibody - LS-C306760 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

HDAC7 Antibody - NBP2-03974 from Novus Biologicals

Prices $279.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HDAC7 Antibody [NBP2-03974] - Western blot analysis of A431 cell lysate using HDAC7 antibody (NBP2-03974) at 5ug/ml.

CC2D1A Antibody - H00054862-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CC2D1A Antibody [H00054862-B01P] - Analysis of CC2D1A expression in human liver.

HDAC10 Antibody - NBP2-03973 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HDAC10 Antibody [NBP2-03973] - analysis of HDAC-10 in HeLa cells using this antibody.
Search more