TPM3

Gene Symbol TPM3
Entrez Gene 7170
Alt Symbol CAPM1, CFTD, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30
Species Human
Gene Type protein-coding
Description tropomyosin 3
Other Description alpha-tropomyosin, slow skeletal|cytoskeletal tropomyosin TM30|epididymis luminal protein 189|epididymis secretory sperm binding protein Li 82p|heat-stable cytoskeletal protein 30 kDa|tropomyosin alpha-3 chain|tropomyosin gamma|tropomyosin-5
Swissprots Q2QD06 Q5VU63 P06753 Q5VU72 Q5VU71 Q9NQH8 Q5VU66 Q969Q2 Q5VU58 D3DV71 P12324 Q8TCG3
Accessions CAD34783 EAW53229 EAW53230 EAW53231 EAW53232 EAW53233 EAW53234 EAW53235 EAW53236 EAW53237 P06753 AA429717 AA863064 AB062125 BAB93457 AF474157 AAL84570 AJ573307 AK026559 AK056889 AK056921 AK056997 BAG51839 AK092690 BAC03946 AK092712 BAC03956 AK123113 AK123571 AK125367 AK298678 BAG60842 AK301674 BAG63147 AK308007 AK315504 BAG37888 AL537561 AY004867 AAF87083 BC000771 AAH00771 BC008407 AAH08407 BC008425 AAH08425 BC015403 AAH15403 BC017195 BC050470 BC062740 AAH62740 BC072428 AAH72428 BC073144 BF967161 BG706843 BI546300 BM674269 BM674651 BQ933569 BU956481 BX419658 BX641075 BX648485 CAI46046 CR997359 DA209890 DA472065 DA894064 DA900740 EU668324 ACF94477 FJ224335 ACI46027 M12128 AAA36775 X04201 CAA27798 X04588 CAB37185 XM_006711515 XP_006711578 XM_006711517 XP_006711580 XM_006711518 XP_006711581 XM_006711519 XP_006711582 XM_006711520 XP_006711583 XM_006711521 XP_006711584 XM_006711522 XP_006711585 XM_006711523 XP_006711586 XM_011509950 XP_011508252 XM_011509951 XP_011508253 XM_011509952 XP_011508254 XM_011509953 XP_011508255 XM_011509954 XP_011508256 NM_001043351 NP_001036816 NM_001043352 NP_001036817 NM_001043353 NP_001036818 NM_001278188 NP_001265117 NM_001278189 NP_001265118 NM_001278190 NP_001265119 NM_001278191 NP_001265120 NM_152263 NP_689476 NM_153649 NP_705935 NR_103460 NR_103461
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Subcellular Location Cytoplasm, cytoskeleton.
Top Pathways Thyroid cancer, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

Anti-Tropomyosin 3 antibody - ab155274 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Tropomyosin 3 antibody (ab155274) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Tropomyosin 3 antibody - ab137798 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Tropomyosin 3 antibody (ab137798) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Tropomyosin 3 antibody - ab76439 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Tropomyosin 3 antibody (ab76439) at 1/500 dilution + immunogen at 0.1 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-Tropomyosin 3 antibody - ab78609 from Abcam

Host Sheep
Clonality Polyclonal

Anti-Tropomyosin 3 antibody [2E4] - ab155406 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2E4
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling Tropomyosin 3 using ab155406 at 20 &microg/ml.

Anti-Tropomyosin 3 antibody [3D5AH3AB4] - ab113692 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D5AH3AB4
Overlay histogram showing A431 cells stained with ab113692 (red line). The cells were fixed with 80% methanol (5 min)/ and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab113692, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2b [PLPV219] (ab91366, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-TPM3 Antibody (aa143-192) - LS-C101891 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TPM3 antibody LS-C101891 Western blot of THP-1 cell lysate.

Anti-TPM3 Antibody - LS-C192467 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TPM3 pAb in extracts from 293T and A431 cells.

Anti-TPM3 Antibody (clone 2E4) IHC-plus™ - LS-B8022 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2E4
Anti-TPM3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8022 dilution 20 ug/ml.

Anti-TPM3 Antibody IHC-plus™ - LS-B11912 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

tropomyosin-3 Antibody - NBP1-57472 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

tropomyosin-3 Antibody - NBP1-87382 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

tropomyosin-3 Antibody - NBP2-29881 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal

tropomyosin-3 Antibody - H00007170-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: tropomyosin-3 Antibody [H00007170-A01] - TPM3 polyclonal antibody (A01), Lot # Abnova060503QCS1 Western Blot analysis of TPM3 expression in HeLa ( Cat # L013V1 ).

tropomyosin-3 Antibody (2E4.) - H00007170-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4.
Immunohistochemistry-Paraffin: tropomyosin-3 Antibody (2E4) [H00007170-M02] - Analysis of monoclonal antibody to TPM3 on formalin-fixed paraffin-embedded human smooth muscle. Antibody concentration 3 ug/ml.

tropomyosin-3 Antibody - NBP2-20732 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

tropomyosin-3 Antibody - 22720002 from Novus Biologicals

Prices $299.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

tropomyosin-3 Antibody (2E4) - H00007170-M02A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2E4

Anti-TPM3 antibody produced in rabbit - HPA009066 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TPM3: <B>Cat. No. HPA009066</B>: Immunohistochemical staining of human smooth muscle shows distinct cytoplasmic positivity.

Monoclonal Anti-TPM3 antibody produced in mouse - SAB1402381 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4
<B>Immunohistochemistry</B><BR/>Monoclonal Anti-TPM3, antibody produced in mouse, clone 2E4, purified immunoglobulin: <B>Cat. No. SAB1402381</B>: Antibody concentration: 3 μg/mL using human smooth muscle tissue.

Anti-TPM3 antibody produced in rabbit - SAB2103438 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TPM3, antibody produced in rabbit: <B>Cat. No. SAB2103438</B>: Immunoblotting analysis of TPM3 in THP-1 cell lysate with TPM3 anitbody at 1 μg/mL.

TPM3 Antibody (OALA06718) - OALA06718 from Aviva Systems Biology

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone [clone 2E4]

TPM3 antibody - middle region (ARP41141_P050) - ARP41141_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Tropomyosin 3 antibody - 70R-4890 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TPM3 Polyclonal Antibody - A1206 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various tissues, using TPM3 antibody.
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