TPM3

Gene Symbol	TPM3
Entrez Gene	7170
Alt Symbol	CAPM1, CFTD, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30
Species	Human
Gene Type	protein-coding
Description	tropomyosin 3
Other Description	alpha-tropomyosin, slow skeletal|cytoskeletal tropomyosin TM30|epididymis luminal protein 189|epididymis secretory sperm binding protein Li 82p|heat-stable cytoskeletal protein 30 kDa|tropomyosin alpha-3 chain|tropomyosin gamma|tropomyosin-5
Swissprots	Q2QD06 Q5VU63 P06753 Q5VU72 Q5VU71 Q9NQH8 Q5VU66 Q969Q2 Q5VU58 D3DV71 P12324 Q8TCG3
Accessions	CAD34783 EAW53229 EAW53230 EAW53231 EAW53232 EAW53233 EAW53234 EAW53235 EAW53236 EAW53237 P06753 AA429717 AA863064 AB062125 BAB93457 AF474157 AAL84570 AJ573307 AK026559 AK056889 AK056921 AK056997 BAG51839 AK092690 BAC03946 AK092712 BAC03956 AK123113 AK123571 AK125367 AK298678 BAG60842 AK301674 BAG63147 AK308007 AK315504 BAG37888 AL537561 AY004867 AAF87083 BC000771 AAH00771 BC008407 AAH08407 BC008425 AAH08425 BC015403 AAH15403 BC017195 BC050470 BC062740 AAH62740 BC072428 AAH72428 BC073144 BF967161 BG706843 BI546300 BM674269 BM674651 BQ933569 BU956481 BX419658 BX641075 BX648485 CAI46046 CR997359 DA209890 DA472065 DA894064 DA900740 EU668324 ACF94477 FJ224335 ACI46027 M12128 AAA36775 X04201 CAA27798 X04588 CAB37185 XM_006711515 XP_006711578 XM_006711517 XP_006711580 XM_006711518 XP_006711581 XM_006711519 XP_006711582 XM_006711520 XP_006711583 XM_006711521 XP_006711584 XM_006711522 XP_006711585 XM_006711523 XP_006711586 XM_011509950 XP_011508252 XM_011509951 XP_011508253 XM_011509952 XP_011508254 XM_011509953 XP_011508255 XM_011509954 XP_011508256 NM_001043351 NP_001036816 NM_001043352 NP_001036817 NM_001043353 NP_001036818 NM_001278188 NP_001265117 NM_001278189 NP_001265118 NM_001278190 NP_001265119 NM_001278191 NP_001265120 NM_152263 NP_689476 NM_153649 NP_705935 NR_103460 NR_103461
Function	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Subcellular Location	Cytoplasm, cytoskeleton.
Top Pathways	Thyroid cancer, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human TMP3 + TRKA protein fragment - ab191465 from Abcam Category Protein Prices $609.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human TPM3 ALK protein fragment - ab190993 from Abcam Category Protein Prices $609.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human Tropomyosin 3 full length protein - ab173022 from Abcam Category Protein Source E. coli Species Human

Human Tropomyosin 3 full length protein - ab116189 from Abcam Category Protein Source E. coli Species Human

Human Tropomyosin 3 protein fragment - ab112675 from Abcam Category Protein Source E. coli Species Human

tropomyosin-3 Recombinant Protein - H00007170-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human tropomyosin-3 Protein - NBP1-78867 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

Tropomyosin 3 Protein - GTX109592-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

TPM3 Protein Lysate (APL10396) - APL10396 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TPM3 Protein Lysate (APL10397) - APL10397 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

Human TPM3 protein - orb169466 from Biorbyt Category Protein Source E. coli

TPM3 protein (His tag) - 80R-2110 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

Tropomyosin 3 Blocking Peptide - 33R-9034 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Tropomyosin-3 (TPM3) (1-248, His-tag) - AR50193PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

Tropomyosin-3 (TPM3) (1-248, His-tag) - AR50193PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

Tropomyosin-3 (TPM3) - H00007170-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Tropomyosin-3 (TPM3) - H00007170-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TPM3, 1-248aa, Human, His tag, E.coli - 01-P1368 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

TPM3, Human, Recombinant - 19-CF21 from ARP American Research Products Category Protein Prices $119.00 Sizes 10 µg Source E. coli Species Human

TPM3 fusion protein - Ag1171 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TPM3 Human - PRPS-1027 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human TPM3 Protein - BP002014-CF21 from Syd Labs Category Protein Prices $126.00, $378.00, $2,880.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human TPM3 Protein - BP002014-PRO-1020 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

TPM3, 1-248aa, Recombinant Protein - GWB-P0670G from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human Tropomyosin 3, His-tagged - TPM3-4853H from Creative Biomart Category Protein

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