TPM3

Gene Symbol TPM3
Entrez Gene 7170
Alt Symbol CAPM1, CFTD, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30
Species Human
Gene Type protein-coding
Description tropomyosin 3
Other Description alpha-tropomyosin, slow skeletal|cytoskeletal tropomyosin TM30|epididymis luminal protein 189|epididymis secretory sperm binding protein Li 82p|heat-stable cytoskeletal protein 30 kDa|tropomyosin alpha-3 chain|tropomyosin gamma|tropomyosin-5
Swissprots Q2QD06 Q5VU63 P06753 Q5VU72 Q5VU71 Q9NQH8 Q5VU66 Q969Q2 Q5VU58 D3DV71 P12324 Q8TCG3
Accessions CAD34783 EAW53229 EAW53230 EAW53231 EAW53232 EAW53233 EAW53234 EAW53235 EAW53236 EAW53237 P06753 AA429717 AA863064 AB062125 BAB93457 AF474157 AAL84570 AJ573307 AK026559 AK056889 AK056921 AK056997 BAG51839 AK092690 BAC03946 AK092712 BAC03956 AK123113 AK123571 AK125367 AK298678 BAG60842 AK301674 BAG63147 AK308007 AK315504 BAG37888 AL537561 AY004867 AAF87083 BC000771 AAH00771 BC008407 AAH08407 BC008425 AAH08425 BC015403 AAH15403 BC017195 BC050470 BC062740 AAH62740 BC072428 AAH72428 BC073144 BF967161 BG706843 BI546300 BM674269 BM674651 BQ933569 BU956481 BX419658 BX641075 BX648485 CAI46046 CR997359 DA209890 DA472065 DA894064 DA900740 EU668324 ACF94477 FJ224335 ACI46027 M12128 AAA36775 X04201 CAA27798 X04588 CAB37185 XM_006711515 XP_006711578 XM_006711517 XP_006711580 XM_006711518 XP_006711581 XM_006711519 XP_006711582 XM_006711520 XP_006711583 XM_006711521 XP_006711584 XM_006711522 XP_006711585 XM_006711523 XP_006711586 XM_011509950 XP_011508252 XM_011509951 XP_011508253 XM_011509952 XP_011508254 XM_011509953 XP_011508255 XM_011509954 XP_011508256 NM_001043351 NP_001036816 NM_001043352 NP_001036817 NM_001043353 NP_001036818 NM_001278188 NP_001265117 NM_001278189 NP_001265118 NM_001278190 NP_001265119 NM_001278191 NP_001265120 NM_152263 NP_689476 NM_153649 NP_705935 NR_103460 NR_103461
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Subcellular Location Cytoplasm, cytoskeleton.
Top Pathways Thyroid cancer, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

Tropomyosin γ CRISPR/Cas9 KO Plasmid (h) - sc-401764 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ HDR Plasmid (h) - sc-401764-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ Double Nickase Plasmid (h) - sc-401764-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ Double Nickase Plasmid (h2) - sc-401764-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ CRISPR Activation Plasmid (h) - sc-401764-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ CRISPR Activation Plasmid (h2) - sc-401764-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ Lentiviral Activation Particles (h) - sc-401764-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ Lentiviral Activation Particles (h2) - sc-401764-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ siRNA (h) - sc-43480 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Tropomyosin γ shRNA Plasmid (h) - sc-43480-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Tropomyosin γ shRNA (h) Lentiviral Particles - sc-43480-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

tropomyosin-3 RNAi - H00007170-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

tropomyosin-3 RNAi - H00007170-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110821 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU097131 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21870 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21870 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11329 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11329

TPM3 siRNA (Human) - CRH4921 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

tropomyosin-3 RNAi - H00007170-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

tropomyosin-3 RNAi - H00007170-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

tropomyosin-3 RNAi - H00007170-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TPM3 - MBS8226360 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Tropomyosin γ CRISPR/Cas9 KO Plasmid (h2) - sc-401764-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tropomyosin γ HDR Plasmid (h2) - sc-401764-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human
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