| Gene Symbol | MAN2A1 |
|---|---|
| Entrez Gene | 4124 |
| Alt Symbol | AMan II, GOLIM7, MANA2, MANII |
| Species | Human |
| Gene Type | protein-coding |
| Description | mannosidase, alpha, class 2A, member 1 |
| Other Description | Golgi alpha-mannosidase II|alpha-mannosidase 2|golgi integral membrane protein 7|mannosidase, alpha type II|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
| Swissprots | Q16767 Q16706 |
| Accessions | EAW49048 Q16706 AK314090 AL833486 BC031659 BC043416 AAH43416 BC111062 BC142656 AAI42657 BC142696 AAI42697 BX341412 BX643508 CR936691 D63998 BAA10017 U31520 AAC50302 XM_011543394 XP_011541696 XM_011543395 XP_011541697 XR_948262 NM_002372 NP_002363 |
| Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Top Pathways | N-Glycan biosynthesis |