| Gene Symbol |
MAN2A1
|
| Entrez Gene |
4124
|
| Alt Symbol |
AMan II, GOLIM7, MANA2, MANII
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mannosidase, alpha, class 2A, member 1
|
| Other Description |
Golgi alpha-mannosidase II|alpha-mannosidase 2|golgi integral membrane protein 7|mannosidase, alpha type II|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
|
| Swissprots |
Q16767 Q16706
|
| Accessions |
EAW49048 Q16706 AK314090 AL833486 BC031659 BC043416 AAH43416 BC111062 BC142656 AAI42657 BC142696 AAI42697 BX341412 BX643508 CR936691 D63998 BAA10017 U31520 AAC50302 XM_011543394 XP_011541696 XM_011543395 XP_011541697 XR_948262 NM_002372 NP_002363
|
| Function |
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
N-Glycan biosynthesis
|