Gene Symbol | MAN2A1 |
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Entrez Gene | 4124 |
Alt Symbol | AMan II, GOLIM7, MANA2, MANII |
Species | Human |
Gene Type | protein-coding |
Description | mannosidase, alpha, class 2A, member 1 |
Other Description | Golgi alpha-mannosidase II|alpha-mannosidase 2|golgi integral membrane protein 7|mannosidase, alpha type II|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
Swissprots | Q16767 Q16706 |
Accessions | EAW49048 Q16706 AK314090 AL833486 BC031659 BC043416 AAH43416 BC111062 BC142656 AAI42657 BC142696 AAI42697 BX341412 BX643508 CR936691 D63998 BAA10017 U31520 AAC50302 XM_011543394 XP_011541696 XM_011543395 XP_011541697 XR_948262 NM_002372 NP_002363 |
Function | Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | N-Glycan biosynthesis |
Human Mannosidase II peptide - ab24441 from Abcam
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Human Mannosidase II protein fragment - ab152509 from Abcam
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MAN2A1 / Mannosidase II Antibody Blocking Peptide - LS-E630 from LifeSpan Bioscience
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MAN2A1 / Mannosidase II Antibody Blocking Peptide - LS-E26552 from LifeSpan Bioscience
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Recombinant Human Alpha-mannosidase II Protein - H00004124-Q01 from Novus Biologicals
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MAN2A1-Antibody-Center-Blocking-peptide - BP10967c from Abgent, a WuXi AppTec company
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MAN2A1 blocking peptide - GTX88874-PEP from GeneTex
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Mannosidase II Peptide - AC21-1390-P from Abcore
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Alpha-Mannosidase 2 / MAN2A1 - H00004124-Q01-10 from Acris Antibodies
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Alpha-Mannosidase 2 / MAN2A1 - H00004124-Q01-25 from Acris Antibodies
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MAN2A1 Peptide - 45-861P from ProSci
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MAN2A1 fusion protein - ag15536 from Proteintech Group
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MAN2A1 fusion protein - ag15950 from Proteintech Group
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Recombinant Human Alpha-mannosidase 2(MAN2A1) ,partial - CSB-YP613697HU CSB-EP613697HU CSB-BP613697HU CSB-MP613697HU from Cusabio
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Alpha-mannosidase 2(MAN2A1) ,partial - MBS1403406 from MyBioSource
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MAN2A1, Peptide - MBS426629 from MyBioSource
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Alpha-mannosidase II Recombinant Protein Antigen - NBP1-89748PEP from Novus Biologicals
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MAN2A1 Peptide, Human - M34GP09136H from Creative Peptides
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MAN2A1 Immunizing peptide - orb50371 from Biorbyt
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Recombinant Human MAN2A1 Protein, GST-tagged - MAN2A1-1427H from Creative Biomart
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