Gene Symbol | CACNG3 |
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Entrez Gene | 10368 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, gamma subunit 3 |
Other Description | TARP gamma-3|neuronal voltage-gated calcium channel gamma-3 subunit|transmembrane AMPAR regulatory protein gamma-3|voltage-dependent calcium channel gamma-3 subunit|voltage-gated calcium channel gamma subunit |
Swissprots | O60359 |
Accessions | AAC15246 EAW55793 EAW55794 O60359 AF100346 AAD22739 AF114832 AAP97231 AF134640 AAF42975 AK055453 BAG51520 AK095553 BAG53082 AK315150 BAG37598 BC033741 BC037899 AAH37899 BC040005 AAH40005 H04803 HQ447969 ADQ32452 NM_006539 NP_006530 |
Function | Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
L-type Ca ++ CP γ3 (C-13) - sc-164818 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ3 (A-07) - sc-81889 from Santa Cruz Biotechnology
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Anti-CACNG3 antibody - ab80992 from Abcam
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Anti-CACNG3 antibody - ab78741 from Abcam
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Anti-CACNG3 Antibody (N-Terminus) - LS-C94053 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56, AP) - LS-C233336 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56, APC) - LS-C233337 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56, Biotin) - LS-C233338 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa162-211) - LS-C135029 from LifeSpan Bioscience
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Anti-CACNG3 Antibody - LS-C26758 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56, FITC) - LS-C233339 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56) - LS-C159254 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56, PE) - LS-C233340 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa28-56, Azide-free, HRP) - LS-C249563 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa199-297) - LS-C306698 from LifeSpan Bioscience
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Anti-CACNG3 Antibody - LS-C306695 from LifeSpan Bioscience
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Anti-CACNG3 Antibody - LS-C309680 from LifeSpan Bioscience
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Anti-CACNG3 Antibody (aa27-56) - LS-C319973 from LifeSpan Bioscience
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CACNG3 Antibody - NBP2-31738 from Novus Biologicals
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CACNG3 Antibody (3E4) - H00010368-M01 from Novus Biologicals
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CACNG3 Antibody - H00010368-B01P from Novus Biologicals
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CACNG3 Antibody - NBP1-30696 from Novus Biologicals
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CACNG3 Polyclonal Antibody - bs-12059R from Bioss
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Rabbit Anti-CACNG3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12059R-A350 from Bioss
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Rabbit Anti-CACNG3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12059R-A488 from Bioss
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