GRM1

Gene Symbol GRM1
Entrez Gene 2911
Alt Symbol GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13
Species Human
Gene Type protein-coding
Description glutamate receptor, metabotropic 1
Other Description metabotropic glutamate receptor 1|protein phosphatase 1, regulatory subunit 85
Swissprots Q13255 F8W805 Q5VTF8 Q5VTF7 Q13256 Q9UGT0 Q9NU10 Q9UGS9 B9EG79 Q14757 Q14758
Accessions EAW47834 EAW47835 Q13255 AB208837 BAD92074 AK308550 BC111844 AAI11845 BC136280 AAI36281 BC143777 BC143779 L76627 AAB05337 L76631 AAB05338 U31215 AAA87843 U31216 AAA87844 XM_011535782 XP_011534084 XM_011535783 XP_011534085 XM_011535784 XP_011534086 NM_001278064 NP_001264993 NM_001278065 NP_001264994 NM_001278066 NP_001264995 NM_001278067 NP_001264996 NM_000838 NP_000829 NM_001114329
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. {ECO:0000269|PubMed:24603153, ECO:0000269|PubMed:7476890}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:24603153}; Multi-pass membrane protein {ECO:0000269|PubMed:24603153}.
Tissue Specificity Detected in brain.
Top Pathways Calcium signaling pathway, Glutamatergic synapse, Long-term depression, Retrograde endocannabinoid signaling, Long-term potentiation

mGluR1 (D5H10) Rabbit mAb - 12551 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5H10
Western blot analysis of extracts from neonatal mouse brain and rat brain using mGluR1 (D5H10) Rabbit mAb.

mGluR1 Antibody - 5310 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

mGluR-1a (C-20) - sc-47128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

mGluR-1a/b (G-13) - sc-47130 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

mGluR-1a/b (N-16) - sc-47131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
mGluR-1a/b (N-16): sc-47131. Western blot analysis of mGluR-1a/b expression in mouse cerebellum (A), rat brain (B) and mouse brain (C) tissue extracts.

mGluR-1a/5 (G-21) - sc-135682 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
mGluR-1a/5 (G-21): sc-135682. Western blot analysis of mGluR-1a/5 expression in rat mGluR-5 (A) and rat mGluR-1a (B) transfected 293 whole cell lysates.

Anti-Metabotropic Glutamate Receptor 1 antibody - ab27199 from Abcam

Prices $378.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Ab27199 at a dilution of 1/50, staining metabolic glutamate recepor 1 in paraffin embedded formalin fixed human brain tissue section.

Anti-Metabotropic Glutamate Receptor 1 antibody - ab90756 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 1 antibody - ab153669 from Abcam

Prices $370.00
Sizes 500 µl
Host Chicken
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 1 antibody - ab105212 from Abcam

Prices $376.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
ab105212 at 15 µg/ml staining Metabotropic Glutamate Receptor 1 in Human brain by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Metabotropic Glutamate Receptor 1 antibody - ab128217 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 1 antibody - ab13037 from Abcam

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab13037 staining human GRM1 in brain neuron, by IHC (formalin fixed paraffin embedded tissues).

Anti-Metabotropic Glutamate Receptor 1 antibody - ab82211 from Abcam

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Metabotropic Glutamate Receptor 1 antibody (ab82211) at 1/1000 dilution + human brain lysate at 20 µgSecondaryAP-conjugated secondary at 1/5000 dilution

Anti-Metabotropic Glutamate Receptor 1 antibody, prediluted - ab27192 from Abcam

Prices $378.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Ab27192, prediluted, staining Metabolic Glutamate Receptor 1 in Paraffin embedded formalin fixed human brain tissue section.

Anti-Metabotropic Glutamate Receptor 1a antibody - ab51314 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Metabotropic Glutamate Receptor 1a staining in rat brain (singulate cortex) using ab51314 at 1/100 dilution. Metabotropic Glutamate Receptor 1a detection was done using anti-rabbit Cy3 conjugated antibodies (red color). DAPI was used to counterstain cell nuclei (blue color).

Anti-Metabotropic Glutamate Receptor 1a antibody [EPR13540] - ab183712 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13540
All lanes : Anti-Metabotropic Glutamate Receptor 1a antibody [EPR13540] (ab183712) at 1/1000 dilutionLane 1 : Mouse brain lysateLane 2 : Rat brain lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-GRM1 / MGLUR1 Antibody (aa1180-1199) - LS-C16520 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-GRM1 / MGLUR1 Antibody (aa1180-1199) - LS-C25607 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-GRM1 / MGLUR1 Antibody - LS-C40779 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GRM1 / MGLUR1 Antibody (C-Terminus) - LS-C72498 from LifeSpan Bioscience

Prices $485.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM1 / MGLUR1 Antibody (C-Terminus) - LS-C26831 from LifeSpan Bioscience

Prices $435.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal
Western blot of mGluR1a receptor antibody on HEK-293 cell lysate.

Anti-GRM1 / MGLUR1 Antibody - LS-C124101 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GRM1 / MGLUR1 Antibody (aa33-522) - LS-C124100 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GRM1 / MGLUR1 Antibody (C-Terminus) - LS-C153486 from LifeSpan Bioscience

Prices $305.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM1 / MGLUR1 Antibody (aa1115-1130) - LS-C187890 from LifeSpan Bioscience

Prices $540.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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