GRM1

Gene Symbol	GRM1
Entrez Gene	2911
Alt Symbol	GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 1
Other Description	metabotropic glutamate receptor 1|protein phosphatase 1, regulatory subunit 85
Swissprots	Q13255 F8W805 Q5VTF8 Q5VTF7 Q13256 Q9UGT0 Q9NU10 Q9UGS9 B9EG79 Q14757 Q14758
Accessions	EAW47834 EAW47835 Q13255 AB208837 BAD92074 AK308550 BC111844 AAI11845 BC136280 AAI36281 BC143777 BC143779 L76627 AAB05337 L76631 AAB05338 U31215 AAA87843 U31216 AAA87844 XM_011535782 XP_011534084 XM_011535783 XP_011534085 XM_011535784 XP_011534086 NM_001278064 NP_001264993 NM_001278065 NP_001264994 NM_001278066 NP_001264995 NM_001278067 NP_001264996 NM_000838 NP_000829 NM_001114329
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. {ECO:0000269|PubMed:24603153, ECO:0000269|PubMed:7476890}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:24603153}; Multi-pass membrane protein {ECO:0000269|PubMed:24603153}.
Tissue Specificity	Detected in brain.
Top Pathways	Calcium signaling pathway, Glutamatergic synapse, Long-term depression, Retrograde endocannabinoid signaling, Long-term potentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Metabotropic Glutamate Receptor 1 protein fragment - ab114707 from Abcam Category Protein Source Wheat germ Species Human

GRM1 / MGLUR1 Antibody Blocking Peptide - LS-E2631 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM1 / MGLUR1 Antibody Blocking Peptide - LS-E29482 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM1 / MGLUR1 Antibody Blocking Peptide - LS-E29484 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM1 / MGLUR1 Antibody Blocking Peptide - LS-E29490 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

mGluR1 Partial Recombinant Protein - H00002911-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

GRM1-Antibody-C-term-Blocking-peptide - BP13701b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

mGLUR1 Blocking Peptide - abx161162 from Abbexa Category Peptide Species Human, Mouse, Rat

mGluR1a / GRM1a - H00002911-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

mGluR1a / GRM1a - H00002911-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human GRM1 - GRM1-29607TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Glutamate Receptor, Metabotropic 1 (GRM1) - RPE821Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

ChemiSCREEN™ Human Recombinant mGlu1 Metabotropic Glutamate Receptor Calcium-Optimized Stable Cell Line - HTS145C from EMD Millipore Species Human

mGLUR1 Blocking Peptide - CBP3661 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Glutamate Receptor, Metabotropic 1 (GRM1) - RPE821Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Glutamate Receptor, Metabotropic 1 Protein (Recombinant) - abx167025 from Abbexa Category Protein Source Human Species Human

mGluR1 Recombinant Protein Antigen - NBP1-89736PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Metabotropic-Glutamate-Receptor-1-Antibody-C-term-Blocking-peptide - BP6341a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRM1 Peptide, Human - M34GP06674H from Creative Peptides Category Peptide Source Synthetic. Species Human

mGLUR1 peptide - orb234536 from Biorbyt Category Peptide Prices $247.00, $536.00 Sizes 1 mg, 5 mg

Recombinant Glutamate Receptor, Metabotropic 1 (GRM1) - RPU53179 from Biomatik Category Protein Prices $194.00, $396.00, $605.00, $721.60 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

GRM1 Recombinant Protein (OPCD03688) - OPCD03688 from Aviva Systems Biology Category Protein Source E.coli Species Human

GRM1 fusion protein - Ag27724 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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