CD79A

Gene Symbol	CD79A
Entrez Gene	973
Alt Symbol	IGA, MB-1
Species	Human
Gene Type	protein-coding
Description	CD79a molecule, immunoglobulin-associated alpha
Other Description	B-cell antigen receptor complex-associated protein alpha chain|CD79a antigen (immunoglobulin-associated alpha)|MB-1 membrane glycoprotein|ig-alpha|membrane-bound immunoglobulin-associated protein|surface IgM-associated protein
Swissprots	A0N775 Q53FB8 P11912
Accessions	AAA20495 AAA57274 CCF76935 CCF76936 EAW57075 EAW57076 P11912 AF283770 AAG15590 AK223371 BAD97091 AK315337 BAG37737 BC018964 BC113731 AAI13732 BC113733 AAI13734 HQ258131 ADR82885 M74721 AAA60270 M80462 AAA59556 M86921 AAA59557 S46706 AAB23558 S75217 AAB20812 S79248 AAC60653 X13451 CAA31802 X83540 CAA58523 NM_001783 NP_001774 NM_021601 NP_067612
Function	Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src- family tyrosine kinases. Represses BCR signaling during development of immature B-cells. {ECO:0000269|PubMed:8617796, ECO:0000269|PubMed:9057631}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. {ECO:0000250}.
Tissue Specificity	B-cells.
Top Pathways	B cell receptor signaling pathway, Primary immunodeficiency

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IgA ELISA Kit (Sandwich ELISA) - LS-F5591 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 1.56-100 ng/ml

Human IgA ELISA Kit (Sandwich ELISA) - LS-F10060 from LifeSpan Bioscience Category ELISA Kit Prices $490.00 Sizes 1 plate Sensitivity 0.24 ng/ml Range 1.56-100 ng/ml

Human IgA ELISA Kit (Sandwich ELISA) - LS-F10551 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 1.56-100 ng/ml

Human CD79A ELISA Kit - RAB0636 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Anti-IgA Antibody BioAssay™ ELISA Kit (Human) - 152280 from USBiological Life Science Category ELISA Kit Sensitivity <0.55ng/ml Range 1.563-100ng/ml

Bovine IgA ELISA kit - 55R-1958 from Fitzgerald Category ELISA Kit Prices $435.00 Sizes 96 tests

Human IgA ELISA kit - 55R-1935 from Fitzgerald Category ELISA Kit Prices $415.00 Sizes 96 tests

Mouse IgA ELISA kit - 55R-1925 from Fitzgerald Category ELISA Kit Prices $375.00 Sizes 96 tests

Rat IgA ELISA kit - 55R-1923 from Fitzgerald Category ELISA Kit Prices $375.00 Sizes 96 tests

Human Anti-Alpha-Fodrin IgG/IgA ELISA Kit - abx053382 from Abbexa Category ELISA Kit

Human Anti-IgA Antibody ELISA Kit - abx052587 from Abbexa Category ELISA Kit

Human Anti-IgA Antibody ELISA Kit - abx150684 from Abbexa Category ELISA Kit Sensitivity 0.55 ng/ml Range 1.563 ng/ml - 100 ng/ml

Anti-Alpha-Fodrin IgG/IgA, α-Fodrin IgG/IgA, Human, ELISA Kit - YHB0217Hu from ARP American Research Products Category ELISA Kit

Anti-alpha-Fodrin IgG/IgA, Human, ELISA Kit - E01A0749 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0u/ml Range 5.0-100 U/ml

Anti-gliadin antibody (IgA), Human, ELISA Kit - CSB-E12028h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Anti-gliadin antibody (IgA), Human, ELISA Kit - E01A2074 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Anti-IgA antibody, Human, ELISA Kit - E01A2080 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Anti-IgA Antibody, Human, ELISA Kit - YHB0280Hu from ARP American Research Products Category ELISA Kit

Anti-saccharomyces cerevisiae antibody (IgA), Human, ELISA Kit - CSB-E15026h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

B-cell antigen receptor complex-associated protein alpha chain (CD79A), Human, ELISA Kit - CSB-EL004957HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

B-cell antigen receptor complex-associated protein alpha chain (CD79A), Human, ELISA Kit - E01B0882 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Bordetella pertussis antibody (IgA), Human, ELISA Kit - CSB-EQ027268HU from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Chlamydia trachomatis antibody (IgA), Human, ELISA Kit - CSB-E17647h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Chlamydia trachomatis antibody (IgA), Human, ELISA Kit - E01C2486 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Helicobacter pylori antibody (IgA), Human, ELISA Kit - CSB-E17034h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Search more