LPCAT3

Gene Symbol	LPCAT3
Entrez Gene	10162
Alt Symbol	C3F, LPCAT, LPLAT 5, LPSAT, MBOAT5, OACT5, nessy
Species	Human
Gene Type	protein-coding
Description	lysophosphatidylcholine acyltransferase 3
Other Description	1-acylglycerophosphocholine O-acyltransferase|1-acylglycerophosphoserine O-acyltransferase|O-acyltransferase (membrane bound) domain containing 5|O-acyltransferase domain-containing protein 5|lyso-PC acyltransferase 3|lyso-PS acyltransferase|lysophosphatidylserine acyltransferase|lysophospholipid acyltransferase 5|membrane bound O-acyltransferase domain containing 5|membrane-bound O-acyltransferase domain-containing protein 5|putative protein similar to nessy
Swissprots	B7Z3N3 Q6P1A2 Q92980 Q9BW40 B2RDH0 Q7KZS1
Accessions	AAB51326 EAW88691 EAW88692 EAW88693 Q6P1A2 AK058063 AK096775 AK296145 BAH12269 AK296164 BAH12270 AK296171 BAH12271 AK311727 AK315538 BAG37917 AM393271 CAL38149 AU125262 BC000664 AAH00664 BC065194 AAH65194 BT007000 AAP35646 BX647983 BX648009 U72515 AAC51640 U72517 NM_005768 NP_005759
Function	Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. {ECO:0000269|PubMed:18195019, ECO:0000269|PubMed:18772128}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:18195019}; Multi-pass membrane protein {ECO:0000269|PubMed:18195019}.
Tissue Specificity	Highly expressed in liver, pancreas and adipose tissue. Very low expression in skeletal muscle and heart. Detected in neutrophils. {ECO:0000269|PubMed:18195019, ECO:0000269|PubMed:18772128}.
Top Pathways	Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MBOAT5 / C3F ELISA Kit (Sandwich ELISA) - LS-F8330 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 1.29 ng/ml Range 3.13-200 ng/ml

Mouse MBOAT5 / C3F ELISA Kit (Sandwich ELISA) - LS-F8440 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 3.13-200 ng/ml

Human MBOAT5 / C3F ELISA Kit (Sandwich ELISA) - LS-F12009 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 3.13-200 ng/ml

Human LPCAT3 ELISA Kit - abx152227 from Abbexa Category ELISA Kit Sensitivity 1.29 ng/ml Range 3.125 ng/ml - 200 ng/ml

Lysophosphatidylcholine Acyltransferase 3 (LPCAT3), Human, ELISA Kit - SEG531Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 1.29ng/mL Range 3.12-200ng/mL

Lysophosphatidylcholine Acyltransferase 3, Human, ELISA Kit - E01L0010 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Lysophospholipid acyltransferase 5, LPCAT3, Human, ELISA Kit - E2212h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS744708 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS753930 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS074517 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS070186 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS746545 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS752448 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

lysophosphatidylcholine acyltransferase 3, ELISA Kit - MBS9339210 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS746067 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS752726 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS748128 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS041582 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS747632 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS750721 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS747399 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS754567 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS062644 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS079541 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 3, ELISA Kit - MBS755650 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

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