MCM3AP

Gene Symbol MCM3AP
Entrez Gene 8888
Alt Symbol GANP, MAP80, SAC3
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 3 associated protein
Other Description 80 kDa MCM3-associated protein|MCM3 acetylating protein|MCM3 acetyltransferase|MCM3 import protein|MCM3 minichromosome maintenance deficient 3 associated protein|germinal center-associated nuclear protein|germinal-center associated nuclear protein|germinal-centre associated nuclear protein
Swissprots Q9UMT4 Q6PJP6 O60318 C9JL56 Q9BSY5 Q2M3C1
Accessions AAS89300 CCQ43242 EAX09296 O60318 AA659734 AB005543 BAA25170 AB011144 BAA25498 AJ010089 CAB52687 AK022303 AK026578 AK095181 BAG53000 AK126313 BAG54306 AK127239 BAG54460 AK304208 BAH14134 AL079407 BC004497 AAH04497 BC013285 AAH13285 BC104958 AAI04959 BC104960 AAI04961 HF584748 CCQ44045 XM_005261203 XP_005261260 XM_005261204 XP_005261261 XM_005261205 XP_005261262 XM_005261206 XP_005261263 XM_006724064 XP_006724127 XR_937577 NM_003906 NP_003897
Function Isoform GANP: Essential for the generation of high- affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation- dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. {ECO:0000250, ECO:0000269|PubMed:22307388}.
Subcellular Location Isoform GANP: Cytoplasm. Nucleus envelope. Nucleus, nuclear pore complex. Note=In B-cells nuclear import depends on interaction with AICDA/AID, and GANP is selectively targeted to the IgV-region gene. {ECO:0000250}.

MCM3AP (E-20) - sc-83297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
MCM3AP (E-20): sc-83297. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.

MCM3AP (G-20) - sc-83298 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

MCM3AP (H-300) - sc-368151 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MCM3AP (H-300): sc-368151. Western blot analysis of MCM3AP expression in K-562 whole cell lysate.

MCM3AP (M-206) - sc-368150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-GANP antibody - ab53083 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab53083 at 1/50 dilution, with and without blocking peptide (ab53083 immunogen)

Anti-GANP antibody - ab113295 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GANP antibody (ab113295) at 0.4 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-GANP antibody - ab41842 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Ab41842 staining human GANP in human tonsil by immunohistochemistry using formalin fixed, paraffin embedded tissue.

Anti-GANP antibody, prediluted - ab41844 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Ab41844 staining human GANP in human tonsil by immunohistochemistry using formalin fixed, paraffin embedded tissue.

Anti-GANP antibody - C-terminal - ab166814 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GANP antibody - C-terminal (ab166814) at 1/500 dilutionLane 1 : COS7 cell extractLane 2 : COS7 cell extract treated with synthesized peptide

Anti-GANP antibody - N-terminal - ab198173 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling GANP with ab198173 at 1/30.

Anti-MCM3AP / GANP Antibody (aa1930-1980) - LS-C289828 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human GANP by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-GANP antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-MCM3AP / GANP Antibody (aa1-50) - LS-C289826 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human GANP by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-GANP antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-MCM3AP / GANP Antibody (Glu1872) - LS-C176034 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of GANP/MCM3AP (E1872) pAb in paraffin-embedded human breast carcinoma tissue.

Anti-MCM3AP / GANP Antibody (aa1841-1890) IHC-plus™ - LS-B8384 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MCM3AP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8384 dilution 5 ug/ml.

Anti-MCM3AP / GANP Antibody (aa297-310) - LS-C47449 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-MCM3AP / GANP Antibody (aa1-150) - LS-C50441 from LifeSpan Bioscience

Prices $530.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
Human tonsil stained with Anti-GANP

Anti-MCM3AP / GANP Antibody (aa1-100) - LS-C308917 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

MCM3AP Antibody - NB100-91779 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: MCM3AP Antibody [NB100-91779] - Extracts from NIH/3T3 cells.

MCM3AP Antibody - NBP1-71883 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCM3AP Antibody [NBP1-71883] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at 0.4 ug/ml.

MCM3AP Antibody - NBP1-71882 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCM3AP Antibody [NBP1-71882] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at 0.4 ug/ml.

MCM3AP Antibody (1H3) - H00008888-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3
Immunocytochemistry/Immunofluorescence: MCM3AP Antibody (1H3) [H00008888-M01] - Analysis of monoclonal antibody to MCM3AP on HeLa cell. Antibody concentration 10 ug/ml.

GANP Polyclonal Antibody - bs-6383R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MCM3AP antibody produced in rabbit - HPA021527 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MCM3AP: <B>Cat. No. HPA021527</B>: Immunohistochemical staining of human colon shows strong cytoplasmic and membranous positivity in glandular cells.

Monoclonal Anti-MCM3AP antibody produced in mouse - WH0008888M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3

MCM3AP Antibody (OAAF01806) - OAAF01806 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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