MCM3AP

Gene Symbol	MCM3AP
Entrez Gene	8888
Alt Symbol	GANP, MAP80, SAC3
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 3 associated protein
Other Description	80 kDa MCM3-associated protein|MCM3 acetylating protein|MCM3 acetyltransferase|MCM3 import protein|MCM3 minichromosome maintenance deficient 3 associated protein|germinal center-associated nuclear protein|germinal-center associated nuclear protein|germinal-centre associated nuclear protein
Swissprots	Q9UMT4 Q6PJP6 O60318 C9JL56 Q9BSY5 Q2M3C1
Accessions	AAS89300 CCQ43242 EAX09296 O60318 AA659734 AB005543 BAA25170 AB011144 BAA25498 AJ010089 CAB52687 AK022303 AK026578 AK095181 BAG53000 AK126313 BAG54306 AK127239 BAG54460 AK304208 BAH14134 AL079407 BC004497 AAH04497 BC013285 AAH13285 BC104958 AAI04959 BC104960 AAI04961 HF584748 CCQ44045 XM_005261203 XP_005261260 XM_005261204 XP_005261261 XM_005261205 XP_005261262 XM_005261206 XP_005261263 XM_006724064 XP_006724127 XR_937577 NM_003906 NP_003897
Function	Isoform GANP: Essential for the generation of high- affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation- dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. {ECO:0000250, ECO:0000269|PubMed:22307388}.
Subcellular Location	Isoform GANP: Cytoplasm. Nucleus envelope. Nucleus, nuclear pore complex. Note=In B-cells nuclear import depends on interaction with AICDA/AID, and GANP is selectively targeted to the IgV-region gene. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GANP protein fragment - ab160246 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human MCM3AP Protein - H00008888-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human Germinal Center-Associated Nuclear Protein protein - orb81137 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

GANP Blocking Peptide - abx063528 from Abbexa Category Peptide Species Human, Mouse, Rat

MCM3AP - H00008888-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCM3AP - H00008888-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GANP fusion protein - ag1486 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Germinal Center-Associated Nuclear Protein - GWB-2DE970 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Species Human

GANP - GWB-260939 from Genway Biotech Category Protein Prices $438.00 Sizes 10 µg

Recombinant Human minichromosome maintenance complex component 3 associated protein, GST-Tagged - MCM3AP-4372H from Creative Biomart Category Protein Source Human

GANP Blocking Peptide - CBP2334 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

GANP (E1872) Peptide - BS1138P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human 80 kDa MCM3-associated protein(MCM3AP) ,partial - CSB-YP013592HU CSB-EP013592HU CSB-BP013592HU CSB-MP013592HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GANP Protein - abx164957 from Abbexa Category Protein Species Human, Mouse, Rat

Germinal Center-Associated Nuclear Protein Human Recombinant - Pr20750 from ProMab Category Protein Prices $175.00, $270.00, $490.00 Sizes 2 μg, 5 μg, 10 μg Source Escherichia Coli. Species Human

MCM3AP Recombinant Protein Antigen - NBP1-83393PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DYNLT1 Protein (OPPA01953) - OPPA01953 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli Species Human

MCM3AP Peptide, Human - M34GP09315H from Creative Peptides Category Peptide Source Synthetic. Species Human

MCM3AP Recombinant Protein Antigen - NBP2-58502PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MCM3AP peptide - orb218197 from Biorbyt Category Peptide Species Human, Mouse, Rat

Search more