S1PR2

Gene Symbol S1PR2
Entrez Gene 9294
Alt Symbol AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2
Species Human
Gene Type protein-coding
Description sphingosine-1-phosphate receptor 2
Other Description S1P receptor 2|S1P receptor EDG5|S1P receptor Edg-5|endothelial differentiation G-protein coupled receptor 5|endothelial differentiation, sphingolipid G-protein-coupled receptor, 5|sphingosine 1-phosphate receptor 2|sphingosine 1-phosphate receptor Edg-5
Swissprots Q86UN8 O95136
Accessions AAP20652 EAW84081 EAW84082 O95136 AF034780 AAC98919 BC069598 AAH69598 BF513287 BG055846 HG510340 XM_011528425 XP_011526727 NM_004230 NP_004221
Function Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

EDG-5 (E-12) - sc-365963 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EDG-5 (E-12): sc-365963. Western blot analysis of EDG-5 expression in NIH/3T3 whole cell lysate.

EDG-5 (F-3) - sc-365589 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EDG-5 (F-3): sc-365589. Western blot analysis of EDG-5 expression in HeLa (A) and IMR-32 (B) whole cell lysates.

EDG-5 (C-16) - sc-16085 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-5 (C-16): sc-16085. Western blot analysis of human recombinant EDG-5 fusion protein.

EDG-5 (H-18) - sc-31577 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EDG-5 (H-18): sc-31577. Western blot analysis of EDG-5 expression in HeLa (A), A-10 (B) and CCD-1064Sk (C) whole cell lysates.

EDG-5 (H-64) - sc-25491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EDG-5 (H-64): sc-25491. Western blot analysis of human recombinant EDG-5 fusion protein.

S1P2/EDG-5/S1PR2 Antibody (368510) [Unconjugated] - MAB3649 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 368510
HEK293 human embryonic kidney cell line transfected with either (A) human S1P2/EDG-5 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human S1P2/EDG-5 Monoclonal Antibody (Catalog # MAB3649) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). Quadrant markers were set based on control antibody staining (Catalog # MAB002). View our protocol for Staining Membrane-associated Proteins.

S1P2/EDG-5/S1PR2 Antibody (368510) [Allophycocyanin] - FAB3649A from Novus Biologicals

Prices $359.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 368510
HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human S1P2/EDG-5 APC-conjugated Monoclonal Antibody (Catalog # FAB3649A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Monoclonal Anti-S1P2, C-Terminal antibody produced in mouse - E4767 from Sigma-Aldrich

Prices $710.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AS65

Anti-S1PR2 antibody produced in goat - SAB2501413 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-S1PR2 <B>Cat. No. SAB2501413</B>: (0.5 μg/mL) staining of Human Frontal Cortex lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-S1P2, C-Terminal antibody produced in rabbit - E7278 from Sigma-Aldrich

Prices $680.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EDG5, C-Terminal antibody produced in rabbit - SAB4503614 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EDG5, C-Terminal: <B>Cat. No. SAB4503614</B>: Immunoblotting analysis of extracts from COLO205 cells, using Anti-EDG5, C-Terminal antibody. The lane on the left was treated with the Anti-EDG5, C-Terminal antibody. The lane on the right (negative control) was treated with both Anti-EDG5, C-Terminal antibody and the synthesized immunogen peptide.

Anti-S1PR2 antibody produced in rabbit - HPA014307 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-S1PR2: <B>Cat. No. HPA014307</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human small intestine shows strong cytoplasmic and membranous positivity in glandular cells.

S1PR2 Antibody - N-terminal region (ARP64815_P050) - ARP64815_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

S1PR2-Antibody-C-term - AP18911b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
S1PR2 Antibody (C-term)(Cat. #AP18911b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the S1PR2 antibody detected the S1PR2 protein (arrow).

S1PR2-Antibody-internal-region - AF3296a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3296a (0.5 µg/ml) staining of Human Frontal Cortex lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

EDG5 antibody - GTX87713 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-EDG5 antibody used in Western blot. GTX87713

EDG5 antibody - GTX87937 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-EDG5 antibody used in Western blot. GTX87937

S1PR2 Antibody - C-terminal region (OAAB14449) - OAAB14449 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Human S1P 2 /EDG-5 APC-conjugated Antibody - FAB3649A from R&D Systems

Prices $359.00
Sizes 100 tests
Host Mouse
Clone 368510
Detection of S1P 2 /EDG-5 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human S1P 2 /EDG-5 APC-conjugated Monoclonal Antibody (Catalog # FAB3649A, filled histogram) or isotype control antibody (Catalog # IC002A , open histogram). View our protocol for Staining Membrane-associated Proteins .

Human S1P 2 /EDG-5 Antibody - MAB3649 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 368510
Detection of S1P 2 /EDG-5 in HEK293 Human Cell Line Transfected with Human S1P 2 /EDG-5 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human S1P 2 /EDG-5 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human S1P 2 /EDG-5 Monoclonal Antibody (Catalog # MAB3649) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B ). Quadrant markers were set based on control antibody staining (Catalog # MAB002 ). View our protocol for Staining Membrane-associated Proteins .

Human S1P2/EDG-5 MAb (Clone 368510), Mouse IgG1 - MAB3649-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 368510

S1PR2 Antibody (OAAF04797) - OAAF04797 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

S1PR2 Antibody (OAAF04874) - OAAF04874 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

EDG5 Antibody (OAAF06333) - OAAF06333 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

EDG5 Antibody (OAAF06334) - OAAF06334 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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