| Gene Symbol |
S1PR2
|
| Entrez Gene |
9294
|
| Alt Symbol |
AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sphingosine-1-phosphate receptor 2
|
| Other Description |
S1P receptor 2|S1P receptor EDG5|S1P receptor Edg-5|endothelial differentiation G-protein coupled receptor 5|endothelial differentiation, sphingolipid G-protein-coupled receptor, 5|sphingosine 1-phosphate receptor 2|sphingosine 1-phosphate receptor Edg-5
|
| Swissprots |
Q86UN8 O95136
|
| Accessions |
AAP20652 EAW84081 EAW84082 O95136 AF034780 AAC98919 BC069598 AAH69598 BF513287 BG055846 HG510340 XM_011528425 XP_011526727 NM_004230 NP_004221
|
| Function |
Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction
|