Gene Symbol | ENTPD8 |
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Entrez Gene | 377841 |
Alt Symbol | E-NTPDase, GLSR2492, NTPDase-8, UNQ2492 |
Species | Human |
Gene Type | protein-coding |
Description | ectonucleoside triphosphate diphosphohydrolase 8 |
Other Description | E-NTPDase 8|liver ecto-ATP-diphosphohydrolase |
Swissprots | A2BG17 Q6UVZ0 Q5MY95 |
Accessions | EAW88389 Q5MY95 AY359088 AAQ89446 AY430414 AAR04374 AY903953 AAW83515 AY903954 AAW83516 BC050293 BC140368 AAI40369 BC141810 AAI41811 BC146509 AAI46510 XM_011518665 XP_011516967 XM_011518666 XP_011516968 XM_011518667 XP_011516969 XM_011518668 XP_011516970 NM_001033113 NP_001028285 NM_198585 NP_940987 |
Function | Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. {ECO:0000269|PubMed:16752921, ECO:0000269|PubMed:17095758}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Epstein-Barr virus infection, Purine metabolism, Pyrimidine metabolism |
Human ENTPD8 full length protein - ab132892 from Abcam
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Human ENTPD8 protein fragment - ab127374 from Abcam
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ENTPD8 Antibody Blocking Peptide - LS-E7758 from LifeSpan Bioscience
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ENTPD8 Antibody Blocking Peptide - LS-E16458 from LifeSpan Bioscience
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Recombinant Human ENTPD8 Protein - H00377841-Q01 from Novus Biologicals
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Recombinant Human ENTPD8 Protein - H00377841-P01 from Novus Biologicals
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ENTPD8-Antibody-C-term-Blocking-Peptide - BP5161b from Abgent, a WuXi AppTec company
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ENTPD8 Blocking Peptide - 33R-4087 from Fitzgerald
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ENTPD8 - H00377841-P01-10 from Acris Antibodies
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ENTPD8 - H00377841-P01-25 from Acris Antibodies
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ENTPD8 - H00377841-Q01-10 from Acris Antibodies
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ENTPD8 - H00377841-Q01-25 from Acris Antibodies
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ENTPD8 fusion protein - ag15306 from Proteintech Group
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ENTPD8 fusion protein - ag15224 from Proteintech Group
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Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 8(ENTPD8) - CSB-YP007697HU CSB-EP007697HU CSB-BP007697HU CSB-MP007697HU from Cusabio
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ENTPD8 (transcript variant 1) - TP318598 from Acris Antibodies
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ENTPD8 Protein - NBP1-82517PEP from Novus Biologicals
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ENTPD8 Peptide, Human - M34GP04962H from Creative Peptides
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Ectonucleoside triphosphate diphosphohydrolase 8 (ENTPD8), Recombinant Protein - MBS1424217 from MyBioSource
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