Gene Symbol | Lipe |
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Entrez Gene | 16890 |
Alt Symbol | 4933403G17Rik, HSL |
Species | Mouse |
Gene Type | protein-coding |
Description | lipase, hormone sensitive |
Other Description | hormone-sensitive lipase |
Swissprots | Q3TE34 P97866 P54310 Q8CDI9 Q6GU16 |
Accessions | AAA50232 AAC53069 AAP84985 EDL24271 EDL24272 P54310 AK016633 BAB30349 AK019846 BAB31878 AK029984 BAC26716 AK169858 BAE41414 BC021642 AAH21642 BC053502 BY513432 U08188 AAC52163 XM_006539570 XP_006539633 XM_006539571 XP_006539634 XM_006539572 XP_006539635 NM_001039507 NP_001034596 NM_010719 NP_034849 |
Function | In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. {ECO:0000269|PubMed:23291629}. |
Subcellular Location | Cell membrane {ECO:0000250}. Membrane, caveola {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. {ECO:0000250}. |
Top Pathways | Insulin signaling pathway, AMPK signaling pathway, cAMP signaling pathway |
Lipe fusion protein - Ag0529 from Proteintech Group
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Recombinant Mouse Hormone-sensitive lipase(Lipe) - CSB-YP012975MO CSB-EP012975MO CSB-BP012975MO CSB-MP012975MO from Cusabio
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Recombinant Mouse LIPE Protein - LIPE-9128M from Creative Biomart
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Hormone-sensitive lipase (Lipe), Recombinant Protein - MBS960375 from MyBioSource
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