Lipe

Gene Symbol Lipe
Entrez Gene 16890
Alt Symbol 4933403G17Rik, HSL
Species Mouse
Gene Type protein-coding
Description lipase, hormone sensitive
Other Description hormone-sensitive lipase
Swissprots Q3TE34 P97866 P54310 Q8CDI9 Q6GU16
Accessions AAA50232 AAC53069 AAP84985 EDL24271 EDL24272 P54310 AK016633 BAB30349 AK019846 BAB31878 AK029984 BAC26716 AK169858 BAE41414 BC021642 AAH21642 BC053502 BY513432 U08188 AAC52163 XM_006539570 XP_006539633 XM_006539571 XP_006539634 XM_006539572 XP_006539635 NM_001039507 NP_001034596 NM_010719 NP_034849
Function In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. {ECO:0000269|PubMed:23291629}.
Subcellular Location Cell membrane {ECO:0000250}. Membrane, caveola {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. {ECO:0000250}.
Top Pathways Insulin signaling pathway, AMPK signaling pathway, cAMP signaling pathway

HSL CRISPR/Cas9 KO Plasmid (m) - sc-421439 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL HDR Plasmid (m) - sc-421439-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL Double Nickase Plasmid (m) - sc-421439-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL Double Nickase Plasmid (m2) - sc-421439-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL CRISPR Activation Plasmid (m) - sc-421439-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL CRISPR Activation Plasmid (m2) - sc-421439-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL Lentiviral Activation Particles (m) - sc-421439-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL Lentiviral Activation Particles (m2) - sc-421439-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HSL siRNA (m) - sc-77404 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

HSL shRNA Plasmid (m) - sc-77404-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

HSL shRNA (m) Lentiviral Particles - sc-77404-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU079111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN34803 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34803 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LIPE siRNA (Mouse) - CRM2353 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse LIPE (NM_010719.5) - SHH330659 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Lipe(NM_010719.5) - SHH150941 from Creative biogene

Category siRNA
Species Reactivities Mouse

LIPE shRNA Plasmid (Mouse) - CHM2353 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

LIPE miRNA 3'UTR clone - MiUTR1M-06669 from Creative biogene

Species Reactivities Mouse
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