PKD1L1

Gene Symbol PKD1L1
Entrez Gene 168507
Alt Symbol PRO19563
Species Human
Gene Type protein-coding
Description polycystic kidney disease 1 like 1
Other Description PC1-like 1 protein|polycystic kidney disease protein 1-like 1|polycystin-1L1
Swissprots Q8TDX9 Q6UWK1
Accessions EAW61003 EAW61004 EAW61005 EAW61006 EAW61007 Q8TDX9 AB061683 BAB85807 AI860869 AY358757 AAQ89117 BF062285 CN283529 XM_011515163 XP_011513465 NM_138295 NP_612152
Function Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning. {ECO:0000269|PubMed:24336289}.
Subcellular Location Cell projection, cilium membrane {ECO:0000269|PubMed:24336289}; Multi-pass membrane protein {ECO:0000269|PubMed:24336289}.
Tissue Specificity Detected in testis and in fetal and adult heart.

PKD1L1 Antibody Blocking Peptide - LS-E23955 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PKD1L1 Recombinant Protein Antigen - NBP1-87220PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PKD1L1 Recombinant Protein Antigen - NBP1-87219PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PKD1L1 Peptide, Human - M34GP11835H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
Search more