PKD1L1

Gene Symbol PKD1L1
Entrez Gene 168507
Alt Symbol PRO19563
Species Human
Gene Type protein-coding
Description polycystic kidney disease 1 like 1
Other Description PC1-like 1 protein|polycystic kidney disease protein 1-like 1|polycystin-1L1
Swissprots Q8TDX9 Q6UWK1
Accessions EAW61003 EAW61004 EAW61005 EAW61006 EAW61007 Q8TDX9 AB061683 BAB85807 AI860869 AY358757 AAQ89117 BF062285 CN283529 XM_011515163 XP_011513465 NM_138295 NP_612152
Function Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning. {ECO:0000269|PubMed:24336289}.
Subcellular Location Cell projection, cilium membrane {ECO:0000269|PubMed:24336289}; Multi-pass membrane protein {ECO:0000269|PubMed:24336289}.
Tissue Specificity Detected in testis and in fetal and adult heart.

Polycystin-1L1 CRISPR/Cas9 KO Plasmid (h) - sc-414908 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 HDR Plasmid (h) - sc-414908-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 Double Nickase Plasmid (h) - sc-414908-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 Double Nickase Plasmid (h2) - sc-414908-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 CRISPR Activation Plasmid (h) - sc-414908-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 CRISPR Activation Plasmid (h2) - sc-414908-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 Lentiviral Activation Particles (h) - sc-414908-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 Lentiviral Activation Particles (h2) - sc-414908-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Polycystin-1L1 siRNA (h) - sc-89442 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Polycystin-1L1 shRNA Plasmid (h) - sc-89442-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Polycystin-1L1 shRNA (h) Lentiviral Particles - sc-89442-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16854 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16854 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04834 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04834

PKD1L1 siRNA (Human) - CRJ6074 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PKD1L1 (NM_138295.3) - SHH376356 from Creative biogene

Category siRNA
Species Reactivities Human

PKD1L1 shRNA Plasmid (Human) - CHJ6074 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PKD1L1 miRNA 3'UTR clone - MiUTR4H-TG06725 from Creative biogene

Species Reactivities Human
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