Gene Symbol | PYCR1 |
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Entrez Gene | 5831 |
Alt Symbol | ARCL2B, ARCL3B, P5C, P5CR, PIG45, PP222, PRO3, PYCR |
Species | Human |
Gene Type | protein-coding |
Description | pyrroline-5-carboxylate reductase 1 |
Other Description | P5C reductase 1|proliferation-inducing protein 45|pyrroline-5-carboxylate reductase 1, mitochondrial |
Swissprots | Q6FHI4 Q9HBQ4 B4DMU0 A6NFM2 P32322 Q96DI6 |
Accessions | ADG28674 EAW89717 EAW89718 EAW89719 EAW89720 EAW89721 EAW89722 EAW89723 EAW89724 EAW89725 EAW89726 P32322 AA026075 AF218000 AAG17242 AK225879 AK297627 BAG60002 AK303852 BAH14067 AL561248 AY513285 AAT08038 BC001504 AAH01504 BC022244 AAH22244 BC071842 AAH71842 CR541769 CAG46568 DA521426 HQ154643 ADU15815 HQ154644 ADU15816 HQ447821 ADQ32305 JF432573 ADZ15790 M77836 AAA36407 XM_005256381 XP_005256438 XM_011523583 XP_011521885 XM_011523584 XP_011521886 XM_011523585 XP_011521887 NM_001282279 NP_001269208 NM_001282280 NP_001269209 NM_001282281 NP_001269210 NM_006907 NP_008838 NM_153824 NP_722546 |
Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. {ECO:0000269|PubMed:16730026, ECO:0000269|PubMed:19648921}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:19648921}. |
Top Pathways | Arginine and proline metabolism, Biosynthesis of amino acids |
Human PYCR1 full length protein - ab101948 from Abcam
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PYCR1 Antibody Blocking Peptide - LS-E21094 from LifeSpan Bioscience
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PYCR1 Antibody Blocking Peptide - LS-E10379 from LifeSpan Bioscience
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PYCR1 Recombinant Protein - H00005831-P01 from Novus Biologicals
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Recombinant Human PYCR1 Protein - NBP1-50895 from Novus Biologicals
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PYCR1-Antibody-C-term-Blocking-Peptide - BP9893b from Abgent, a WuXi AppTec company
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PYCR1 Protein (OPPA02522) - OPPA02522 from Aviva Systems Biology
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Human PYCR1 protein - orb244478 from Biorbyt
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Human PYCR1 protein - orb169125 from Biorbyt
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PYCR1 Blocking Peptide - 33R-4559 from Fitzgerald
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PYCR1 Blocking Peptide - 33R-8196 from Fitzgerald
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PYCR1 protein (His tag) - 80R-1572 from Fitzgerald
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PYCR1 (1-319, His-tag) - AR09751PU-L from Acris Antibodies
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PYCR1 (1-319, His-tag) - AR09751PU-N from Acris Antibodies
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PYCR1 - H00005831-P01-10 from Acris Antibodies
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PYCR1 - H00005831-P01-25 from Acris Antibodies
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Pyrroline-5-Carboxylate Reductase 1, Human Recombinant - 228-12188-1 from RayBiotech
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Recombinant Human Pyrroline-5-Carboxylate Reductase 1 - 228-12188-2 from RayBiotech
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Recombinant Human Pyrroline-5-Carboxylate Reductase 1 - 228-12188-3 from RayBiotech
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PYCR1, 1-319aa, Human, His tag, E.coli - 01-PYCR-1 from ARP American Research Products
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PYCR1 fusion protein - ag17919 from Proteintech Group
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PYCR1 fusion protein - Ag3764 from Proteintech Group
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PYCR1 fusion protein - ag17745 from Proteintech Group
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PYCR1 fusion protein - Ag17854 from Proteintech Group
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PYCR1 Human - ENPS-042 from NeoScientific
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